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Obesity Does Not Impact Perioperative or Postoperative Outcomes in Patients with Inflammatory Bowel Disease

  • Original Article
  • Published:
Journal of Gastrointestinal Surgery

Abstract

Background

While the prevalence of obesity in IBD patients is rapidly increasing, it is unclear if obesity impacts surgical outcomes in this population. We aim to investigate the effects of BMI on perioperative and postoperative outcomes in IBD patients by stratifying patients into BMI groups and comparing outcomes between these groups.

Methods

This is a retrospective cohort study where IBD patients who underwent intestinal surgeries between the years of 2000 to 2014 were identified. The patients were divided into groups based on BMI: underweight (BMI <18.5), normal weight (BMI 18.5–24.9), overweight (BMI 25–29.9), and obese (BMI ≥30). Preoperative patient demographics, operative variables, and postoperative complications were collected and compared between BMI groups.

Results

A total of 391 surgeries were reviewed (34 underweight, 187 normal weight, 105 overweight, and 65 obese) from 325 patients. No differences were observed in preoperative patient demographics, type of IBD, preoperative steroid or biologic mediator use, or mean laboratory values. No differences were observed in percent operative procedures with anastomosis, surgeries converted to open, estimated blood loss, intraoperative complications, and median operative time. Thirty-day postoperative complication rates including total complications, wound infection, or anastomotic leak were similar between groups. There was a statistically significant increased postoperative bleeding risk (p = 0.029) in underweight patients. The relative percent for increased postoperative bleeding risk between BMI groups was as follows: 2.9 % in underweight, zero in normal weight, 2.9 % in overweight, and zero in obese.

Conclusion

Obesity does not appear to impact intraoperative variables nor does obesity appear to worsen postoperative complication rates in IBD patients.

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Acknowledgments

The project described was partially supported by the National Institutes of Health through Grant Number UL1-TR-000005.

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Authors and Affiliations

  1. Department of Surgery, University of Pittsburgh, Pittsburgh, PA, 15213, USA

    Jesse Guardado, Ashley E. Danicic, Javier Salgado, Andrew R. Watson, James P. Celebrezze, David S. Medich & Jennifer Holder-Murray

  2. Division of General Surgery, University of Wisconsin, Madison, WI, 53792, USA

    Evie Carchman

  3. Division of Colon and Rectal Surgery, University of Pittsburgh Medical Center, 3471 5th Ave. Kaufmann Medical Building, Suite 603, Pittsburgh, PA, 15213, USA

    Ashley E. Danicic, Javier Salgado, Andrew R. Watson, James P. Celebrezze, David S. Medich & Jennifer Holder-Murray

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  1. Jesse Guardado
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  2. Evie Carchman
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  3. Ashley E. Danicic
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  4. Javier Salgado
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  8. Jennifer Holder-Murray
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Corresponding author

Correspondence to Jennifer Holder-Murray.

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Financial Support

No financial support was used for this retrospective study. Statistical support through the Clinical and Translational Science Institute (CTSI) at the University of Pittsburgh was utilized. The CTSI is supported by the National Institutes of Health through Grant Number UL1-TR-000005.

Part of this work was presented in a poster at the American Society of Colon and Rectal Surgeons annual meeting in 2014 at Hollywood, FL (5/17/2014–5/21/2014).

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Guardado, J., Carchman, E., Danicic, A.E. et al. Obesity Does Not Impact Perioperative or Postoperative Outcomes in Patients with Inflammatory Bowel Disease. J Gastrointest Surg 20, 725–733 (2016). https://doi.org/10.1007/s11605-015-3060-4

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  • DOI: https://doi.org/10.1007/s11605-015-3060-4

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