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Validation of an English Version of the Padova Quality of Life Instrument to Assess Quality of Life Following Ileal Pouch Anal Anastomosis

  • 2008 ssat poster presentation manuscript
  • Published:
Journal of Gastrointestinal Surgery Aims and scope

Abstract

Objective

Ileal pouch anal anastomosis (IPAA) is the procedure of choice for most patients requiring surgery for ulcerative colitis and familial adenomatous polyposis because of its perceived improvement in health-related quality of life (HRQL). The aims of this cross-sectional study were to validate an English version of the Padova Inflammatory Bowel Disease Quality of Life questionnaire (PIBDQL) in patients undergoing IPAA and to investigate the pre- and postoperative predictors of long-term HRQL.

Materials and Methods

In May 2005, the English version of the PIBDQL, Short Inflammatory Bowel Disease Questionnaire, and the SF-36 were mailed to 1,379 patients who underwent IPAA at the Mount Sinai Hospital between 1982 and 2004. The test–retest reliability, internal consistency, construct validity, and discriminative ability of the English version of the PIBDQL were assessed.

Results

Nine hundred fifty-five patients (69%) (475 female, 480 male; mean, age 43 years) returned the questionnaires. The mean PIBDQL score was 21.1 (3.4), suggesting good quality of life. Test–retest reliability [intraclass correlation coefficient (ICC) = 0.784] and internal consistency (Cronbach’s α = 0.83) were good. Construct validity and discriminative ability of the English version of PIBDQL were adequate. Multivariate analysis revealed that women (p < 0.01) and Crohn’s disease patients (p < 0.01) had significantly worse PIBDQL scores.

Conclusions

The English version PIBDQL is a reliable and valid disease-specific instrument for assessing quality of life in patients with IPAA. In this series, female gender and CD were significant predictors of worse HRQL.

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Authors and Affiliations

  1. Department of Surgery, Veneto Oncological Institute (IOV-IRCCS), Padova, Italy

    Marco Scarpa

  2. Department of Surgery, University of Toronto, Toronto, ON, Canada

    Brenda I. O’Connor, Zane Cohen & Robin S. McLeod

  3. Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada

    Robin S. McLeod

  4. Digestive Disease Research Centre and Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada

    Brenda I. O’Connor, Zane Cohen & Robin S. McLeod

  5. Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada

    Charles J. Victor

  6. Mount Sinai Hospital, Room 449, 600 University Avenue, Toronto, M5G 1X4, Canada

    Robin S. McLeod

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  1. Marco Scarpa
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  2. Charles J. Victor
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  3. Brenda I. O’Connor
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  4. Zane Cohen
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  5. Robin S. McLeod
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Correspondence to Robin S. McLeod.

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Scarpa, M., Victor, C.J., O’Connor, B.I. et al. Validation of an English Version of the Padova Quality of Life Instrument to Assess Quality of Life Following Ileal Pouch Anal Anastomosis. J Gastrointest Surg 13, 416–422 (2009). https://doi.org/10.1007/s11605-008-0775-5

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  • DOI: https://doi.org/10.1007/s11605-008-0775-5

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