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Application of full-field organ dose modulation on cervical- thoraco-abdominopelvic contrast-enhanced computed tomography

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Japanese Journal of Radiology Aims and scope Submit manuscript

Abstract

Background and objective

To study the radiation dose and image quality on the use of full-field organ dose modulation (ODM) on cervical-thoracic-abdominal-pelvic contrast-enhanced computed tomography (CT) scanning on female chemotherapy patients.

Methods

Eighty female chemotherapy patients undergoing cervical-thoracic-abdominal-pelvic contrast-enhanced CT were prospectively enrolled and randomly divided into two groups: group A and group B, each with 40 patients. Full-field ODM technique was used on group A and regular scanning patterns were used on group B. We calculated and recorded the signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), subjective scores, mean tube currents of the anterior, left, posterior, and right aspects of the thyroid, breast, and ovary layers of all the images. The CT dose index volume (CTDIvol) and dose-length product (DLP) of each patient were recorded and the effective radiation dose (ED) was calculated. The above data were statistically analyzed.

Results

There were no statistically significant differences in the SNR, CNR, and image quality scores of the thyroid, breast, and ovary layers of groups A and B during the arterial and venous phases (P > 0.05). The tube current on the anterior, left, posterior, and right aspects of the thyroid, breast, and ovary layers during the arterial and venous phases (thyroid: 324.46 ± 53.2 and 327.97 ± 61.34; breast: 243.13 ± 50.04 and 248.32 ± 60.33; ovary: 332.28 ± 71.50 and 339.78 ± 76.69; respectively) of group A were (statistically) significantly lower than those of group B (thyroid: 407.60 ± 96.81 and 402.73 ± 90.15; breast: 313.00 ± 106.68 and 315.20 ± 106.73; ovary: 457.78 ± 106.56 and 459.63 ± 106.27; respectively) (P < 0.05). The respective mean CTDIvol and DLP in group A were 22% and 24% lower than those of group B. The mean EDs of the neck, chest, and abdominal-pelvic region in group A were 19.3%, 21.4%, and 26.4% lower than those of group B, respectively (P < 0.05).

Conclusion

The use of ODM can reduce radiation dose of female chemotherapy patients undergoing cervical-thoracic-abdominal-pelvic contrast-enhanced CT, especially radiation-sensitive organs, while maintaining overall image quality.

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Funding

This study was funded by Key R&D projects of Hebei Province (grant number: 20377765D), Hebei province program of training and basic project of clinical medicine of China (grant number: 361007), Postgraduate Innovation Project of Hebei University (grant number: hbu2019ss037), and the affiliated hospital of Hebei university outstanding youth foundation (grant numbers: 2015Q002 and 2015Q017).

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Authors and Affiliations

  1. Department of Radiology, The Affiliated Hospital of Hebei University, Baoding, 071000, People’s Republic of China

    Yongxia Zhao, Dongxue Li, Tianle Zhang & Yize Xu

  2. Department of Radiology, Baoding No.2 hospital, Baoding, 071000, People’s Republic of China

    Xue Geng

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  1. Yongxia Zhao
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Correspondence to Yongxia Zhao.

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We declare that we do not have any commercial or associative interest that represents a conflict of interest in connection with the work submitted.

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This article does not contain any studies with animals performed by any of the authors.

Ethical approval

All procedures performed in our study involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study. All patients signed informed consent. This prospective study received institutional board approval from the affiliated hospital of Hebei University and each participant provided informed consent.

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Zhao, Y., Geng, X., Li, D. et al. Application of full-field organ dose modulation on cervical- thoraco-abdominopelvic contrast-enhanced computed tomography. Jpn J Radiol 39, 254–260 (2021). https://doi.org/10.1007/s11604-020-01056-7

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  • DOI: https://doi.org/10.1007/s11604-020-01056-7

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