Abstract
Purpose
This study evaluated the calcium blooming-reducing effect and the differences of luminal diameter among various-energy virtual monochromatic images (VMIs) using rapid kilovolt-switching dual-energy computed tomography (DECT).
Materials and methods
Forty-five calcified segments in 31 patients were analyzed. For the analysis, 40- to 140-keV VMIs on both non-contrast CT and coronary CT angiography were generated at 10-keV steps, and calcification size and luminal diameter were measured using CT number profile curve and full-width at half-maximum method. We compared calcification size and luminal diameter on each keV VMIs with those on 70-keV VMI.
Results
There was no significant differences among the 40- to 140-keV VMIs regarding calcification size or luminal diameter.
Conclusion
The 40- to 140-keV VMIs produced by single-source DECT had no effect on the calcification size or luminal diameter in the coronary artery.
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References
Cordeiro MA, Miller JM, Schmidt A, Lardo AC, Rosen BD, Bush DE, et al. Non-invasive half millimetre 32 detector row computed tomography angiography accurately excludes significant stenoses in patients with advanced coronary artery disease and high calcium scores. Heart. 2006;92:589–97.
Hamon M, Morello R, Riddell JW, Hamon M. Coronary arteries: diagnostic performance of 16- versus 64-section spiral CT compared with invasive coronary angiography–meta-analysis. Radiology. 2007;245:720–31.
Meijboom WB, Meijs MF, Schuijf JD, Cramer MJ, Mollet NR, van Mieghem CA, et al. Diagnostic accuracy of 64-slice computed tomography coronary angiography: a prospective, multicenter, multivendor study. J Am Coll Cardiol. 2008;52:2135–44.
Budoff MJ, Dowe D, Jollis JG, Gitter M, Sutherland J, Halamert E, et al. Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease: results from the prospective multicenter ACCURACY (Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive Coronary Angiography) trial. J Am Coll Cardiol. 2008;52:1724–32.
Ong TK, Chin SP, Liew CK, Chan WL, Seyfarth MT, Liew HB, et al. Accuracy of 64-row multidetector computed tomography in detecting coronary artery disease in 134 symptomatic patients: influence of calcification. Am Heart J. 2006;151(1323):e1–6.
Gottlieb I, Miller JM, Arbab-Zadeh A, Dewey M, Clouse ME, Sara L, et al. The absence of coronary calcification does not exclude obstructive coronary artery disease or the need for revascularization in patients referred for conventional coronary angiography. J Am Coll Cardiol. 2010;55:627–34.
Arbab-Zadeh A, Miller JM, Rochitte CE, Dewey M, Niinuma H, Gottlieb I, et al. Diagnostic accuracy of computed tomography coronary angiography according to pre-test probability of coronary artery disease and severity of coronary arterial calcification. The CORE-64 (Coronary Artery Evaluation Using 64-Row Multidetector Computed Tomography Angiography) International Multicenter Study. J Am Coll Cardiol. 2012;59:379–87.
Hoffmann U, Ferencik M, Cury RC, Pena AJ. Coronary CT angiography. J Nucl Med. 2006;47:797–806.
Tanaka R, Yoshioka K, Muranaka K, Chiba T, Ueda T, Sasaki T, et al. Improved evaluation of calcified segments on coronary CT angiography: a feasibility study of coronary calcium subtraction. Int J Cardiovasc Imaging. 2013;29(Suppl 2):75–81.
Yunaga H, Ohta Y, Kaetsu Y, Kitao S, Watanabe T, Furuse Y, et al. Diagnostic performance of calcification-suppressed coronary CT angiography using rapid kilovolt-switching dual-energy CT. Eur Radiol. 2017;27:2794–801.
Pessis E, Campagna R, Sverzut JM, Bach F, Rodallec M, Guerini H, et al. Virtual monochromatic spectral imaging with fast kilovoltage switching: reduction of metal artifacts at CT. Radiographics. 2013;33:573–83.
Stehli J, Fuchs TA, Singer A, Bull S, Clerc OF, Possner M, et al. First experience with single-source, dual-energy CCTA for monochromatic stent imaging. Eur Heart J Cardiovasc Imaging. 2015;16:507–12.
Almutairi A, Sun Z, Al Safran Z, Poovathumkadavi A, Albader S, Ifdailat H. Optimal scanning protocols for dual-energy CT angiography in peripheral arterial stents: an in vitro phantom study. Int J Mol Sci. 2015;16:11531–49.
Mannelli L, MacDonald L, Mancini M, Ferguson M, Shuman WP, Ragucci M, et al. Dual energy computed tomography quantification of carotid plaques calcification: comparison between monochromatic and polychromatic energies with pathology correlation. Eur Radiol. 2015;25:1238–46.
Silva AC, Morse BG, Hara AK, Paden RG, Hongo N, Pavlicek W. Dual-energy (spectral) CT: applications in abdominal imaging. Radiographics. 2011;31:1031–46.
Hausleiter J, Meyer T, Hermann F, Hadamitzky M, Krebs M, Gerber TC, et al. Estimated radiation dose associated with cardiac CT angiography. JAMA. 2009;301:500–7.
Matsumoto K, Jinzaki M, Tanami Y, Ueno A, Yamada M, Kuribayashi S. Virtual monochromatic spectral imaging with fast kilovoltage switching: improved image quality as compared with that obtained with conventional 120-kVp CT. Radiology. 2011;259:257–62.
Scheske JA, O’Brien JM, Earls JP, Min JK, LaBounty TM, Cury RC, et al. Coronary artery imaging with single-source rapid kilovolt peak-switching dual-energy CT. Radiology. 2013;268:702–9.
Leipsic J, Abbara S, Achenbach S, Cury R, Earls JP, Mancini GJ, et al. SCCT guidelines for the interpretation and reporting of coronary CT angiography: a report of the Society of Cardiovascular Computed Tomography Guidelines Committee. J Cardiovasc Comput Tomogr. 2014;8:342–58.
Schneider CA, Rasband WS, Eliceiri KW. NIH Image to ImageJ: 25 years of image analysis. Nat Methods. 2012;9:671–5.
Groen JM, Greuter MJ, van Ooijen PM, Oudkerk M. A new approach to the assessment of lumen visibility of coronary artery stent at various heart rates using 64-slice MDCT. Eur Radiol. 2007;17:1879–84.
Kanda Y. Investigation of the freely available easy-to-use software ‘EZR’ for medical statistics. Bone Marrow Transplant. 2013;48:452–8.
Vavere AL, Arbab-Zadeh A, Rochitte CE, Dewey M, Niinuma H, Gottlieb I, et al. Coronary artery stenoses: accuracy of 64-detector row CT angiography in segments with mild, moderate, or severe calcification–a subanalysis of the CORE-64 trial. Radiology. 2011;261:100–8.
André F, Korosoglou G, Hosch W, Giannitsis E, Kauczor HU, Katus HA, et al. Performance of dual source versus 256-slice multi-slice CT in the evaluation of 16 coronary artery stents. Eur J Radiol. 2013;82:601–7.
Steen H, André F, Korosoglou G, Mueller D, Hosch W, Kauczor HU, et al. In vitro evaluation of 56 coronary artery stents by 256-slice multi-detector coronary CT. Eur J Radiol. 2011;80:143–50.
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All authors have contributed to the study conception and design. Conceptualization and methodology: HY, YO; data curation: HY, JK, SK, and MI; formal analysis, investigation, writing—original draft preparation: HY; writing—review and editing: YO and SF; supervision: SF. All authors read and approved the final manuscript.
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
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This single-center retrospectively study protocol was approved by the institutional ethics committee, and written informed consent was waived.
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Yunaga, H., Ohta, Y., Kishimoto, J. et al. Effect of energy difference in the evaluation of calcification size and luminal diameter in calcified coronary artery plaque using spectral CT. Jpn J Radiol 38, 1142–1149 (2020). https://doi.org/10.1007/s11604-020-01027-y
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DOI: https://doi.org/10.1007/s11604-020-01027-y