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Additive value of 320-section low-dose dynamic volume CT in relation to 3-T MRI for the preoperative evaluation of brain tumors

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Abstract

Purpose

To assess whether 320-section low-dose dynamic volume computed tomography (320-LDVCT) with adaptive iterative dose reduction (AIDR) adds value to 3-T MRI for the preoperative evaluation of brain tumors.

Methods

The study population was comprised of 16 consecutive patients with brain tumors who, in addition to preoperative 3-T MRI, underwent 320-LDVCT with AIDR. Two radiologists independently evaluated the CT and MRI studies; one measured the relative cerebral blood volume (rCBV) in the tumor and contralateral brain on CT and MR perfusion maps. Interobserver agreement was assessed by κ statistics.

Results

In 3 of 16 patients (19 %), 320-LDVCT added diagnostic value to 3-T MRI studies with respect to the visualization of feeders (κ = 0.77), and in 12 (75 %) it helped the delineation of venous structures (κ = 0.71) and the relationship between the tumor and adjacent vessels (κ = 0.85). The average standardized rCBV value was 12.2 ± 2.40 (range 0.7–36.6) on MR and 8.80 ± 2.77 (range 0.8–38.0) on CT perfusion studies; the correlation between these values was very strong (r = 0.92, p < 0.0001). According to the neurosurgeons, 320-LDVCT added helpful information for surgery in 4 patients (25 %).

Conclusion

The 320-LDVCT can add value to 3-T MRI for the tumor feeders and relationship between the tumor and adjacent vessels.

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Abbreviations

AIDR:

Adaptive iterative dose reduction

320-LDVCT:

320-Section low-dose dynamic volume CT

rCBV:

Relative cerebral blood volume

MRI:

Magnetic resonance imaging

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Authors and Affiliations

  1. Departments of Diagnostic Radiology, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556, Japan

    Eri Hayashida, Masafumi Kidoh, Minako Azuma, Yasuhiko Iryo, Mika Kitajima, Seitaro Oda, Daisuke Utsunomiya, Takeshi Nakaura & Yasuyuki Yamashita

  2. Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, 860-8556, Japan

    Hideo Nakamura

  3. Department of Radiology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan

    Toshinori Hirai

Authors
  1. Eri Hayashida
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  2. Toshinori Hirai
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  3. Hideo Nakamura
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  4. Masafumi Kidoh
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  5. Minako Azuma
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  6. Yasuhiko Iryo
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  7. Mika Kitajima
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  8. Seitaro Oda
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  9. Daisuke Utsunomiya
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  10. Takeshi Nakaura
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  11. Yasuyuki Yamashita
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Corresponding author

Correspondence to Masafumi Kidoh.

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Conflict of interest

E. H, T. H, H. N, M. K, M. A, Y. I, M. K, S. O, D. U, T. N, Y. Y: None.

Financial disclosure

E. H, T. H, H. N, M. K, M. A, Y. I, M. K, S. O, D. U, T. N, Y. Y: None.

We declare that all human and animal studies have been approved by the Kumamoto University ethics committee and have therefore been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. We declare that all patients gave informed consent prior to inclusion in this study.

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Hayashida, E., Hirai, T., Nakamura, H. et al. Additive value of 320-section low-dose dynamic volume CT in relation to 3-T MRI for the preoperative evaluation of brain tumors. Jpn J Radiol 34, 691–699 (2016). https://doi.org/10.1007/s11604-016-0576-9

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  • DOI: https://doi.org/10.1007/s11604-016-0576-9

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