Skip to main content
SpringerLink
Log in

Prenatal diagnosis of total arhinia by MRI

  • Case Report
  • Published:
Japanese Journal of Radiology Aims and scope Submit manuscript

Abstract

Congenital arhinia is the absence of an external nose, nasal cavities and olfactory apparatus, and extremely rare. It occurs during the early gestational stage and may be a result of maldevelopment of the paired nasal placodes embryologically. Total arhinia is often associated with other craniofacial abnormalities. Early detection may be helpful for the parents and physician. However, fewer than 40 patients with arhinia have been reported so far, and most of them were diagnosed after birth. To our knowledge, this is the first case diagnosed by fetal MRI during the second trimester of pregnancy, and confirmed by pathological examination.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Albernaz VS, Castillo M, Mukherji SK, et al. Congenital arhinia. AJNR Am J Neuroradiol. 1996;17:1312–4.

    CAS  PubMed  Google Scholar 

  2. Cusick W, Sullivan CA, Rojas B. Prenatal diagnosis of total arhinia. Ultrasound Obstet Gynecol. 2000;15:259–61.

    Article  CAS  PubMed  Google Scholar 

  3. Majewski S, Donnenfeld AE, Kuhlman K, Patel A. Second-trimester prenatal diagnosis of total arhinia. J Ultrasound Med. 2007;26:391–5.

    PubMed  Google Scholar 

  4. McGlone L. Congenital arhinia. J Ped Child Health. 2003;39:474–6.

    Article  CAS  Google Scholar 

  5. Kazan-Tannus JF, Levine D, McKenzie C, et al. Real-time magnetic resonance imaging aids prenatal diagnosis of isolated cleft palate. J Ultrasound Med. 2005;24:1533–40.

    PubMed  Google Scholar 

  6. Cohen D, Goitein KJ. Arhinia revisted. Rhinology. 1987;25:237–44.

    CAS  PubMed  Google Scholar 

  7. Sato D, Shimokawa O, Harada N, et al. Congenital arhinia: molecular-genetic analysis of five patients. Am J Med Genet A. 2007;143:546–52.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiology, Nanjing Medical University Affiliated Suzhou Hospital, 26 Daoqian Road, Suzhou, Jiangsu, China

    Xiaobing Li

  2. Centre for Medical Ultrasound, Nanjing Medical University Affiliated Suzhou Hospital, Suzhou, Jiangsu, China

    Lili Zhang

  3. Department of Pathology, Nanjing Medical University Affiliated Suzhou Hospital, Suzhou, Jiangsu, China

    Feng Wang

Authors
  1. Xiaobing Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Lili Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Feng Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Xiaobing Li.

Ethics declarations

Conflict of interest

No conflict of interest exits in the manuscript.

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Li, X., Zhang, L. & Wang, F. Prenatal diagnosis of total arhinia by MRI. Jpn J Radiol 33, 672–674 (2015). https://doi.org/10.1007/s11604-015-0473-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11604-015-0473-7

Keywords

Search

Navigation