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Results of surgery plus postoperative radiotherapy for patients with malignant parotid tumor

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Japanese Journal of Radiology Aims and scope Submit manuscript

Abstract

Purpose

The latest version of the World Health Organization (WHO) histologic classification of salivary gland malignancies was published in 2005. To contribute to data accumulation on the basis of this latest version, a retrospective study was performed.

Materials and methods

Participants comprised 27 patients who underwent postoperative radiotherapy between 2000 and 2013. Two, eight, and 17 patients were allocated to low, intermediate, and high-grade groups, respectively, in accordance with the latest WHO classification. The radiation field included the tumor bed and ipsilateral regional lymph nodes for 25 patients. The radiation dose was 46–60 Gy (median 56 Gy).

Results

Median duration of follow-up was 41 months. Five-year locoregional control was 89 %. Two patients experienced local recurrence and 7 patients developed distant metastases. No patients in the low or intermediate-grade groups developed distant metastases. Overall 3 and 5-year survival for all patients were 81 and 75 %, respectively. Five-year overall survival for patients in the low and intermediate-grade groups was 100 %, compared with 59 % for patients in the high-grade group (p = 0.03).

Conclusion

Favorable locoregional control was achieved for patients with malignant parotid tumors who underwent surgery plus postoperative radiotherapy. Patients with high-grade tumors frequently experienced distant metastases and prognosis was poor.

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Authors and Affiliations

  1. Department of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka City University, 1-4-3, Asahimachi, Abeno-ku, Osaka, 5458585, Japan

    Shogo Matsuda, Masako Hosono, Hideyuki Morimoto, Eiichiro Okazaki, Kosuke Amano, Yoshitaka Miki, Shinichi Tsutsumi, Yasuhiko Shimatani & Yukio Miki

  2. Department of Radiation Oncology, Graduate School of Medicine, Osaka City University, 1-4-3, Asahimachi, Abeno-ku, Osaka, 5458585, Japan

    Shogo Matsuda, Masako Hosono, Hideyuki Morimoto, Eiichiro Okazaki, Kosuke Amano, Yoshitaka Miki, Shinichi Tsutsumi, Yasuhiko Shimatani & Yukio Miki

  3. Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, Osaka City University, 1-4-3, Asahimachi, Abeno-ku, Osaka, 5458585, Japan

    Hiroyoshi Iguchi

  4. Department of Radiology, Izumi Municipal Hospital, 4-10-10, Fuchucho, Izumi, 5940071, Japan

    Takuhito Tada

  5. Department of Diagnostic Pathology, Graduate School of Medicine, Osaka City University, 1-4-3, Asahimachi, Abeno-ku, Osaka, 5458585, Japan

    Masahiko Osawa & Yuuko Kuwae

Authors
  1. Shogo Matsuda
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  2. Hiroyoshi Iguchi
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  3. Takuhito Tada
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  4. Masako Hosono
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  5. Masahiko Osawa
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  6. Yuuko Kuwae
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  7. Hideyuki Morimoto
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  8. Eiichiro Okazaki
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  9. Kosuke Amano
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  10. Yoshitaka Miki
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  11. Shinichi Tsutsumi
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  12. Yasuhiko Shimatani
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  13. Yukio Miki
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Corresponding author

Correspondence to Shogo Matsuda.

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The authors declare that they have no conflict of interest.

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All applicable institutional guidelines for the care were followed.

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Matsuda, S., Iguchi, H., Tada, T. et al. Results of surgery plus postoperative radiotherapy for patients with malignant parotid tumor. Jpn J Radiol 33, 533–537 (2015). https://doi.org/10.1007/s11604-015-0450-1

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  • DOI: https://doi.org/10.1007/s11604-015-0450-1

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