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Clinical study of the application of SPECT, CT, and SPECT/CT for diagnosing rib diseases

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Abstract

Objective

To evaluate the practical application of SPECT, CT, and SPECT/CT to the diagnosis of rib diseases, and to compare their accuracies in differentiating benign and malignant rib diseases.

Materials and methods

SPECT, CT, and SPECT/CT were applied to 237 patients. 190 cases in total, with 305 focal lesions, agreed to clinical follow-up. Statistically significant differences (p < 0.05) were observed among these imaging modalities when their diagnosis agreement ratios (i.e., the percentage of correct diagnoses achieved using a particular imaging modality) were compared.

Results

For the 81 cases that were confirmed to be malignant, the diagnosis agreement ratios of SPECT, CT, and SPECT/CT were 55.56, 76.54, and 92.59 %, respectively, which were significantly different (p < 0.05). For the 97 cases that were confirmed to be benign, the diagnosis agreement ratios of SPECT, CT, and SPECT/CT were 50.52, 83.51, and 92.78 %, respectively. For the benign cases, the diagnosis agreement ratio of SPECT was significantly different (p < 0.05) from those of CT and SPECT/CT, while the diagnosis agreement ratio of CT was not significantly different (p > 0.05) from that of SPECT/CT.

Conclusions

SPECT/CT fusion imaging yielded significantly improved diagnostic accuracy for rib lesions compared with SPECT or CT alone. SPECT/CT provides markedly more detailed information that is useful for rib lesion diagnosis.

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Acknowledgments

We are very grateful for the support provided by the First People’s Hospital of Xiaoshan, Hangzhou, Zhejiang Province, China, and Zhongshan Hospital, Fudan University, Shanghai, China. We would like to express our wholehearted appreciation to the doctors and experts who helped us with this study. Those generous doctors and experts include Dr. Yushen Gu, Dr. Yan Xiu, Dr. Beilei Li, Dr. Weimin Zhu, Dr. Yiqiu Zhang, Dr. Shuguang Chen, and other anonymous persons. Funding was kindly provided by the First People’s Hospital of Xiaoshan, Hangzhou, Zhejiang Province, China.

Conflict of interest

There are no conflicts of interest.

Ethical standard

Informed consent was obtained individually from all of the participants who were included in this study. All of the procedures performed in this study were carried out in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The study was also approved by the institutional review board.

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Authors and Affiliations

  1. Department of Radiology, The First People’s Hospital of Xiaoshan, Hangzhou, 311200, Zhejiang Province, China

    Runqing Duan

  2. Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China

    Hongcheng Shi

Authors
  1. Runqing Duan
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  2. Hongcheng Shi
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Corresponding author

Correspondence to Runqing Duan.

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Duan, R., Shi, H. Clinical study of the application of SPECT, CT, and SPECT/CT for diagnosing rib diseases. Jpn J Radiol 33, 131–139 (2015). https://doi.org/10.1007/s11604-015-0390-9

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  • DOI: https://doi.org/10.1007/s11604-015-0390-9

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