Skip to main content

Advertisement

Log in

Rim-enhancing breast masses with smooth or spiculated margins on magnetic resonance imaging: histopathology and clinical significance

  • Pictorial Essay
  • Published:
Japanese Journal of Radiology Aims and scope Submit manuscript

Abstract

Rim enhancement is defined as enhancement that is more pronounced at the periphery of a mass. It can have varying appearances, ranging from a thin pattern to one that is thicker. This internal enhancement characteristic is an established characteristic of malignant lesions. Additionally, the use of combined descriptors, especially internal enhancement characteristics and the associated margin, can provide a more powerful predictive value than that of individual descriptors. The margin assessment of rim-enhancing masses is important and can vary in appearance from smooth to spiculated. Moreover, rim enhancement may be dynamic in that it changes appearance during the dynamic phases of contrast- enhanced breast magnetic resonance imaging (ce-MRI), and this feature can lead to confusion in the correct application of this lexicon. Rim-enhancing masses on ce-MRI are typically of two morphological types (i.e., a thin rim-enhancing mass with a smooth margin and a thick rim-enhancing mass with a spiculated margin). It is helpful to review and clarify the lexicon of rim enhancement using combined descriptors based on the pathological findings as doing so can help predict the likelihood of malignancy of ce-MRI lesions.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Nunes LW, Schnall MD, Siegelman ES, Langlotz CP, Orel SG, Sullivan D, et al. Diagnostic performance characteristics of architectural features revealed by high spatial-resolution MR imaging of the breast. AJR Am J Roentgenol 1997;169:409–415.

    PubMed  CAS  Google Scholar 

  2. Orel SG, Schnall MD. MR imaging of the breast for the detection, diagnosis, and staging of breast cancer. Radiology 2001;220:13–30.

    PubMed  CAS  Google Scholar 

  3. Schnall MD, Blume J, Bluemke D, DeAngelis GA, DeBruhl N, Harms S, et al. Diagnostic architectural and dynamic features at breast MR imaging: multicenter study. Radiology 2006;238:42–53.

    Article  PubMed  Google Scholar 

  4. American College of Radiology. Breast imaging reporting and data system: magnetic resonance imaging (BI-RADS-MRI). 1st edn. Reston, VA: American College of Radiology; 2003.

    Google Scholar 

  5. Buadu LD, Murakami J, Murayama S, Hashiguchi N, Sakai S, Toyoshima S, et al. Patterns of peripheral enhancement in breast masses: correlation of findings on contrast medium enhanced MRI with histologic features and tumor angiogenesis. J Comput Assist Tomogr 1997;21:421–430.

    Article  PubMed  CAS  Google Scholar 

  6. Sherif H, Mahfouz AE, Oellinger H, Hadijuana J, Blohmer JU, Taupitz M, et al. Peripheral washout sign on contrastenhanced MR images of the breast. Radiology 1997;205:209–213.

    PubMed  CAS  Google Scholar 

  7. Matsubayashi R, Matsuo Y, Edakuni G, Satoh T, Tokunaga O, Kudo S. Breast masses with peripheral rim enhancement on dynamic contrast-enhanced MR images: correlation of MR findings with histologic features and expression of growth factors. Radiology 2000;217:841–848.

    PubMed  CAS  Google Scholar 

  8. Marklund M, Trop-Pedersen S, Bentzon N, Thomsen C, Roslind A, Nolsoe CP. Contrast kinetics of the malignant breast tumor-border versus center enhancement on dynamic midfield MRI. Eur J Radiol 2008;65:279–285.

    Article  PubMed  Google Scholar 

  9. Kobayashi M, Kawashima H, Matsui O, Zen Y, Suzuki M, Inokuchi M, et al. Two different types of ring-like enhancement on dynamic MR imaging in breast cancer: correlation with the histopathologic findings. J Magn Reson Imaging 2008;28:1435–1443.

    Article  PubMed  Google Scholar 

  10. Lee SH, Cho N, Kim SJ, Cha JH, Cho KS, Ko ES, et al. Correlation between high resolution dynamic MR features and prognostic factors in breast cancer. Korean J Radiol 2008;9:10–18.

    Article  PubMed  Google Scholar 

  11. Uematsu T, Kasami M, Yuen S. Triple negative breast cancer: correlation between the MR findings and the pathological findings. Radiology 2009;250:638–647.

    Article  PubMed  Google Scholar 

  12. Gutierrez RL, DeMartini WB, Eby PR, Kurland BF, Peacock S, Lehman CD. BI-RADS lesion characteristics predict likelihood of malignancy in breast MRI for masses but not for nonmasslike enhancement. AJR Am J Roentgenol 2009;193:994–1000.

    Article  PubMed  Google Scholar 

  13. Okafuji T, Yabuuchi H, Sakai S, Soeda H, Matsuo Y, Inoue T, et al. MR imaging features of pure mucinous carcinoma of the breast. Eur J Radiol 2006;60:405–413.

    Article  PubMed  Google Scholar 

  14. Velasco M, Santamaría G, Ganau S, Farrús B, Zanón G, Romagosa C, et al. MRI of metaplastic carcinoma of the breast. AJR Am J Roentgenol 2005;184:1274–1278.

    PubMed  Google Scholar 

  15. Hasebe T, Tsuda H, Hirohashi S, Shimosato Y, Tsubono Y, Yamamoto H, et al. Fibrotic focus in infiltrating ductal carcinoma of the breast: a significant histopathological prognostic parameter for predicting the long-term survival of the patients. Breast Cancer Res Treat 1998;49:195–208.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Takayoshi Uematsu.

About this article

Cite this article

Uematsu, T., Kasami, M. & Nicholson, B.T. Rim-enhancing breast masses with smooth or spiculated margins on magnetic resonance imaging: histopathology and clinical significance. Jpn J Radiol 29, 609–614 (2011). https://doi.org/10.1007/s11604-011-0612-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11604-011-0612-8

Key words

Navigation