Skip to main content

Advertisement

SpringerLink
Log in

Multidetector-row computed tomography findings of sclerosing mesenteritis with associated diseases and its prevalence

  • Original Article
  • Published:
Japanese Journal of Radiology Aims and scope Submit manuscript

Abstract

Purpose

Our aim was to report the multidetector-row computed tomography (MDCT) findings of sclerosing mesenteritis, which is a rare disease characterized by chronic nonspecific inflammation of mesenteric adipose tissue. It has associated diseases, and we explored its prevalence.

Materials and methods

A total of 2100 patients were evaluated retrospectively for sclerosing mesenteritis between December 2007 and May 2009. Signs and symptoms, associated diseases, laboratory data, surgical histories, and related findings of a misty mesentery, which corresponds to sclerosing mesenteritis on MDCT, were recorded.

Results

Misty mesentery findings were seen in 51 (2.43%; 35 men) patients. Their ages ranged between 33 and 78 years (mean 56.2 years). The most frequent complaint of patients was abdominal pain (n = 19; 37.2%). The most prominent possible causative and/or associated factors in our study were malignancy (n = 9; 17.6%), previous surgery (n = 17; 33.3%), smoking (n = 20; 39.2%), coronary artery disease (n = 9; 17.6%), urolithiasis (n = 10; 19.6%), hypertension (n = 18; 35.2%), hyperlipidemia (n = 13; 25.5%), and diabetes mellitus (n = 11; 21.5%). On MDCT, density values in mesenteric fat (−62.8 ± 18.6 HU) were significantly higher than the values for subcutaneous (−103.9 ± 5.8 HU) and retroperitoneal (−105 ± 6 HU) fatty tissues (both P < 0.0001). A partially hyperdense stripe (n = 37; 72.6%), well-defined soft tissue nodules (100%), hypodense fatty halo enclosing vessels (n = 1; 1.9%), and nodules (n = 12; 23.5%) were demonstrated in most of the patients.

Conclusion

The diagnosis of sclerosing mesenteritis has increased with the more frequent use of MDCT and the popularization of the DICOM viewer. Defined hallmarks on MDCT can be helpful for differentiating sclerosing mesenteritis from other pathologies.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Daskalogiannaki M, Voloudaki A, Prassopoulos P, Magkanas E, Stefanaki K, Apostalaki E, et al. CT evaluation of mesenteric panniculitis: prevalence and associated diseases. AJR Am J Roentgenol 2000;174:427–431.

    PubMed  CAS  Google Scholar 

  2. Ogden WW 2nd, Bradburn DM, Rives JD. Mesenteric panniculitis: review of 27 cases. Ann Surg 1965;161:864–875.

    Article  PubMed  Google Scholar 

  3. Horton KM, Lawler LP, Fishman EK. CT findings in sclerosing mesenteritis (panniculitis): spectrum of disease. Radiographics 2003;23:1561–1567.

    Article  PubMed  Google Scholar 

  4. González CI, Cires M, Rubio T, Jiménez FJ, García de Eulate I, Artondo MT. [A case of mesenteric panniculitis.] An Sist Sanit Navar 2008;31:81–85.

    PubMed  Google Scholar 

  5. Vettoretto N, Diana DR, Poiatti R, Matteucci A, Chioda C, Giovanetti M. Occasional finding of mesenteric lipodystrophy during laparoscopy: a difficult diagnosis. World J Gastroenterol 2007;13:5394–5396.

    PubMed  Google Scholar 

  6. Hakgüder G, Akgür FM, Olguner M, Ozer E, Aktug T. A case of mesenteric panniculitis in a 4-year-old child. Pediatr Int 2000;42:577–578.

    Article  PubMed  Google Scholar 

  7. Joerger M, Nuessli DF, Henz S, Zaunbauer W, Cerny T, Cogliatti SB, et al. CT-diagnosed mesenteric alterations in patients with non-Hodgkin’s lymphoma: a population-based study. Onkologie 2008;31:514–519.

    Article  PubMed  Google Scholar 

  8. Kebapçi M, Adapinar B, Kaya T, Kebapçi N. [Mesenteric panniculitis of the colon: barium enema, US, CT, and MRI findings (case report).] Tani Girisim Radyol 2004;10:284–288.

    PubMed  Google Scholar 

  9. Van Breda Vriesman AC, Schuttevaer HM, Coerkamp EG, Puylaert JB. Mesenteric panniculitis: US and CT features. Eur Radiol 2004;14:2242–8.

    Article  PubMed  Google Scholar 

  10. Rosón N, Garriga V, Cuadrado M, Pruna X, Carbó S, Vizcaya S, et al. Sonographic findings of mesenteric panniculitis: correlation with CT and literature review. J Clin Ultrasound 2006;34:169–176.

    Article  PubMed  Google Scholar 

  11. Wat SY, Harish S, Winterbottom A, Choudhary AK, Freeman AH. The CT appearances of sclerosing mesenteritis and associated diseases. Clin Radiol 2006;61:652–658.

    Article  PubMed  CAS  Google Scholar 

  12. Ghanem N, Pache G, Bley T, Kotter E, Langer M. MR findings in a rare case of sclerosing mesenteritis of the mesocolon. J Magn Reson Imaging 2005;21:632–636.

    Article  PubMed  Google Scholar 

  13. Levy AD, Rimola J, Mehrotra AK, Sobin LH. From the archives of the AFIP: benign fibrous tumors and tumorlike lesions of the mesentery: radiologic-pathologic correlation. Radiographics 2006;26:245–264.

    Article  PubMed  Google Scholar 

  14. Seo BK, Ha HK, Kim AY, Kim TK, Kim MJ, Byun JH, et al. Segmental misty mesentery: analysis of CT features and primary causes. Radiology 2003;226:86–94.

    Article  PubMed  Google Scholar 

  15. Mindelzun RE, Jeffrey RB Jr, Lane MJ, Silverman PM. The misty mesentery on CT: differential diagnosis. AJR Am J Roentgenol 1996;167:61–65.

    PubMed  CAS  Google Scholar 

  16. Aschoff AJ. MDCT of the abdomen. Eur Radiol 2006;16(suppl 7):M54–M57.

    PubMed  Google Scholar 

  17. Emory TS, Monihan JM, Carr NJ, Sobin LH. Sclerosing mesenteritis, mesenteric panniculitis and mesenteric lipodystrophy: a single entity? Am J Surg Pathol 1997;21:392–398.

    Article  PubMed  CAS  Google Scholar 

  18. Sabate JM, Torrubia S, Maideu J, Franquet T, Monill JM, Perez C. Sclerosing mesenteritis: imaging findings in 17 patients. AJR Am J Roentgenol 1999;172:625–629.

    PubMed  CAS  Google Scholar 

  19. Delgado Plasencia L, Rodriguez Ballester L, Lopez-Tomassetti Fernandez EM, Hernandez Morales A, Carrillo Pallares A, Hernandez Siverio N. Mesenteric panniculitis: experience in our centre. Rev Esp Enferm Dig 2007;99:291–297.

    Article  PubMed  CAS  Google Scholar 

  20. Gu GL, Wang SL, Wei XM, Ren L, Li DC, Zou FX. Sclerosing mesenteritis as a rare cause of abdominal pain and intraabdominal mass: a cases report. Cases J 2008;1:242.

    Article  PubMed  Google Scholar 

  21. Issa I, Baydoun H. Mesenteric panniculitis: various presentations and treatment regimens. Worl J Gastroenterol 2009;15:3827–3830.

    Article  Google Scholar 

  22. Kipfer RE, Moertel CG, Dahlin DC. Mesenteric lipodystrophy. Ann Intern Med 1974;80:583–588.

    Google Scholar 

  23. Paul G, Schaffler A, Neumeier M, Fürst A, Bataillle F, Buechler C, et al. Profiling adipocytokine secretion from creeping fat in Crohn’s disease. Inflamm Bowel Dis 2006;12:471–477.

    Article  PubMed  Google Scholar 

  24. Polyzos SA, Kountouras J, Zavos C. Nonalcoholic fatty liver disease: the pathogenetic roles of insulin resistance and adipocytokines. Curr Mol Med 2009;9:229–314.

    Article  Google Scholar 

  25. Schaffler A, Schölmerich J, Büchler C. Mechanisms of disease: adipocytokines and visceral adipose tissue: emerging role in nonalcoholic fatty liver disease. Nat Clin Pract Gastroenterol Hepatol 2005;2:273–280.

    Article  PubMed  Google Scholar 

  26. John BJ, Irukulla S, Abulafi AM, Kumar D, Mendall MA. Systematic review: adipose tissue, obesity and gastrointestinal diseases. Aliment Pharmacol Ther 2006;23:1511–1523.

    Article  PubMed  CAS  Google Scholar 

  27. Li H, Lelliott C, Hakansson P, Ploj K, Tuneld A, Verolin-Johansson M, et al. Intestinal, adipose, and liver inflammation in diet-induced obese mice. Metabolism 2008;57:1704–1710.

    Article  PubMed  CAS  Google Scholar 

  28. Ferrari TCA, Couto CM, Vilaca TS, Xavier MAP, Faria LC. An unusual presentation of mesenteric panniculitis. Clinics 2008;63:843–844.

    Article  PubMed  Google Scholar 

  29. Iwanicki-Caron I, Savoye G, Legros JR, Savoye-Collet C, Herve S, Lerebour E. Successful management of symptoms of steroid-dependent mesenteric panniculitis with colchicine. Dig Dis Sci 2006;51;1245–1249.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiology, Ankara Ataturk Training and Research Hospital, Bilkent, Ankara, 06800, Turkey

    Murat Canyigit

  2. Department of Radiology, Bayindir Hospital, Sogutozu, Ankara, Turkey

    Ali Koksal, Ayca Akgoz, Murat Sarisahin & Okan Akhan

  3. Department of Radiology, Beyhekim State Hospital, Selçuklu, Konya, Turkey

    Taylan Kara

Authors
  1. Murat Canyigit
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Ali Koksal
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Ayca Akgoz
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Taylan Kara
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Murat Sarisahin
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Okan Akhan
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Murat Canyigit.

About this article

Cite this article

Canyigit, M., Koksal, A., Akgoz, A. et al. Multidetector-row computed tomography findings of sclerosing mesenteritis with associated diseases and its prevalence. Jpn J Radiol 29, 495–502 (2011). https://doi.org/10.1007/s11604-011-0587-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11604-011-0587-5

Key words

Search

Navigation