Abstract
Malignant transformation or tumor rupture is a rare complication of ovarian mature cystic teratomas. We present computed tomography (CT) images of a 52-year-old woman that revealed a large, predominantly cystic mass filled with fat and enhanced solid components located in the lower abdomen. Ten days later, the cystic mass ruptured, and massive ascites was observed on magnetic resonance imaging (MRI). Resulting from the rupture, MRI revealed reduced size and thickening wall of the tumor. After resection, the mass ruptured, and malignant transformation (squamous cell carcinoma) was observed. To our knowledge, there are no reports describing before and after images of a ruptured cystic teratoma with malignant transformation.
Similar content being viewed by others
References
Rha SE, Byun JY, Jung SE, Kim HL, Oh SN, Kim H, et al. Atypical CT and MRI manifestations of mature ovarian cystic teratomas. AJR Am J Roentgenol 2004;183:743–750.
Fibus TF. Intraperitoneal rupture of a benign cystic ovarian teratoma: findings at CT and MRI imaging. AJR Am J Roentgenol 2000;174:261–262.
Takemori M, Nishimura R. MRI findings of an ovarian dermoid cyst with malignant transformation. Magn Reson Med Sci 2003;2:105–108.
Phupong V, Sueblinvong T, Triratanachat S. Ovarian teratoma with diffused peritoneal reactions mimicking advanced ovarian malignancy. Arch Gynecol Obstet 2004;270:189–191.
Abitbol MM, Pomerance W, Mackles A. Spontaneous intra-peritoneal rupture of benign cystic teratomas: review of literature and report of two cases. Obstet Gynecol 1959;13:198–203.
Wang PC, Yang TL, Pan HB. CT images of a malignant-transformed ovarian mature cystic teratoma with rupture. Korean J Radiol 2008; 9:458–461.
Maslin P, Luchs JS, Haas J, Katz DS. Ovarian teratoma with malignant transformation: CT diagnosis. AJR Am J Roentgenol 2002;178:1574.
Lai PF, Hsieh SC, Chien JC, Fang CL, Chan WP, Yu C. Malignant transformation of an ovarian mature cystic teratoma: computed tomography findings. Arch Gynecol Obstet 2005;271:355–357.
Kikkawa U, Nawa A, Tamakoshi K, Ishikawa H, Kuzuya K, Suganuma N, et al. Diagnosis of squamous cell carcinoma arising from mature cystic teratoma of the ovary. Cancer 1998;82:2249–2255.
Kido A, Togashi K, Konishi I, Kataoka ML, Koyama T, Ueda H, et al. Dermoid cysts of ovary with malignant transformation: MR appearance. AJR 1999;172:445–449.
Author information
Authors and Affiliations
Corresponding author
About this article
Cite this article
Hosokawa, T., Sato, Y., Seki, T. et al. Malignant transformation of a mature cystic teratoma of the ovary with rupture. Jpn J Radiol 28, 372–375 (2010). https://doi.org/10.1007/s11604-010-0434-0
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11604-010-0434-0