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Extrapancreatic neural plexus invasion by carcinomas of the pancreatic head region: evaluation using thin-section helical CT

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Abstract

Purpose

The aim of this study was to determine the computed tomographic (CT) criteria for diagnosing the second portion of the extrapancreatic neural plexus (PLX-II) invasion by carcinoma of the pancreatic head region on thin-section helical CT.

Materials and methods

A total of 41 patients with carcinoma of the pancreatic head region (17 in the pancreas, 24 in the lower common bile duct) underwent three-phase helical CT (collimation 5 mm; reconstruction 2.5 mm) before surgery. Two criteria were established for the assessment of the PLX-II running between the superior mesenteric artery (SMA) and the medial margin of the uncinate process: criterion A: assessment of the area around the SMA and inferior pancreaticoduodenal artery; criterion B: assessment of the jejunal trunk.

Results

PLX-II invasion was pathologically confirmed in 19 patients with pancreatobiliary carcinoma. For criterion A, all 19 patients with positive PLX-II invasion and 20 of the 22 with negative PLX-II invasion were correctly diagnosed (sensitivity 100%; specificity 91%; accuracy 95%). For criterion B, 3 of the 17 patients with positive PLX-II invasion and all 20 with negative PLX-II invasion were correctly diagnosed (sensitivity 18%; specificity 100%; accuracy 62%). The two false-positive cases using criterion A were correctly diagnosed using criterion B.

Conclusion

Thin-section helical CT provides sufficient diagnostic ability regarding PLX-II invasion by carcinoma of the pancreatic head region.

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Authors and Affiliations

  1. Department of Radiology, Oita University Faculty of Medicine, Hasama-machi, Yufu, Oita, 879-5593, Japan

    Hui Tian, Hiromu Mori, Shunro Matsumoto, Yasunari Yamada & Hiro Kiyosue

  2. First Department of Surgery, Oita University Faculty of Medicine, Oita, Japan

    Masayuki Ohta & Seigo Kitano

Authors
  1. Hui Tian
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  2. Hiromu Mori
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  3. Shunro Matsumoto
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  4. Yasunari Yamada
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  5. Hiro Kiyosue
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  6. Masayuki Ohta
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  7. Seigo Kitano
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Corresponding author

Correspondence to Hiromu Mori.

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Tian, H., Mori, H., Matsumoto, S. et al. Extrapancreatic neural plexus invasion by carcinomas of the pancreatic head region: evaluation using thin-section helical CT. Radiat Med 25, 141–147 (2007). https://doi.org/10.1007/s11604-006-0115-1

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  • DOI: https://doi.org/10.1007/s11604-006-0115-1

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