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Quantitative assessment of regional left ventricular wall thickness and thickening using 16 multidetector-row computed tomography: comparison with cine magnetic resonance imaging

Radiation Medicine volume 25, pages 119–126 (2007)Cite this article

Abstract

Purpose

The purpose of this study was to investigate the feasibility of retrospective electrocardiography-gated multidetector-row computed tomography (MDCT) in the assessment left ventricular (LV) wall thickness and thickening and to test its validity compared to cine magnetic resonance imaging (MRI) as a standard of reference.

Materials and methods

We enrolled 19 patients who underwent both cardiac MDCT and cine MRI. End-diastolic wall thickness (EDWT) and end-systolic wall thickness (ESWT) were measured in 16 myocardial segments. Percent systolic wall thickening (%SWT) was generated from the EDWT and ESWT. Nondiagnostic myocardial segments were excluded. Correlation and agreement between MDCT and cine MRI were analyzed.

Results

Segmental assessability values were 86.2% (262/304) and 92.1% (280/304) for MDCT and cine MRI, respectively. In assessable segments by both modalities (80.9%, 246/304), a significant correlation between MDCT and MRI was found (r = 0.89, 0.85, and 0.61, for EDWT, ESWT, and %SWT, respectively; all P < 0.05). Mean EDWT and ESWT values by MDCT were slightly lower than those by cine MRI (9.8 ± 3.6 vs. 10.0 ± 3.7 mm and 13.8 ± 4.4 vs. 14.1 ± 4.3 mm, respectively; both P < 0.01). Bland-Altman analysis revealed acceptable limits of agreement between MDCT and Cine MRI.

Conclusion

MDCT is a feasible method to assess regional LV wall thickness and systolic thickening.

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Authors and Affiliations

  1. Department of Radiology, Ehime University Postgraduate School of Medicine, Shitsukawa, Toon, 791-0295, Japan

    Rene E. Kanza, Hiroshi Higashino, Teruhito Kido, Yoshifumi Sugawara & Teruhito Mochizuki

  2. Department of Cardiology, Ehime University Postgraduate School of Medicine, Shitsukawa, Toon, Japan

    Akira Kurata & Makoto Saito

Authors
  1. Rene E. Kanza
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  2. Hiroshi Higashino
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  3. Teruhito Kido
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  4. Akira Kurata
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  5. Makoto Saito
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  6. Yoshifumi Sugawara
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  7. Teruhito Mochizuki
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Corresponding author

Correspondence to Teruhito Mochizuki.

Additional information

Part of this study was presented at the 1st Annual Meeting of the Society of Cardiovascular CT in cooperation with the 7th International Conference on Cardiac CT, Washington, DC, July 13–16, 2006

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Kanza, R., Higashino, H., Kido, T. et al. Quantitative assessment of regional left ventricular wall thickness and thickening using 16 multidetector-row computed tomography: comparison with cine magnetic resonance imaging. Radiat Med 25, 119–126 (2007). https://doi.org/10.1007/s11604-006-0113-3

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  • DOI: https://doi.org/10.1007/s11604-006-0113-3

Key words

  • Multislice computed tomography (CT)
  • Magnetic resonance imaging (MRI)
  • Left ventricular wall thickness
  • Systolic thickening