Advertisement

Radiation Medicine

, Volume 25, Issue 3, pp 119–126 | Cite as

Quantitative assessment of regional left ventricular wall thickness and thickening using 16 multidetector-row computed tomography: comparison with cine magnetic resonance imaging

  • Rene E. Kanza
  • Hiroshi Higashino
  • Teruhito Kido
  • Akira Kurata
  • Makoto Saito
  • Yoshifumi Sugawara
  • Teruhito MochizukiEmail author
ORIGINAL ARTICLE

Abstract

Purpose

The purpose of this study was to investigate the feasibility of retrospective electrocardiography-gated multidetector-row computed tomography (MDCT) in the assessment left ventricular (LV) wall thickness and thickening and to test its validity compared to cine magnetic resonance imaging (MRI) as a standard of reference.

Materials and methods

We enrolled 19 patients who underwent both cardiac MDCT and cine MRI. End-diastolic wall thickness (EDWT) and end-systolic wall thickness (ESWT) were measured in 16 myocardial segments. Percent systolic wall thickening (%SWT) was generated from the EDWT and ESWT. Nondiagnostic myocardial segments were excluded. Correlation and agreement between MDCT and cine MRI were analyzed.

Results

Segmental assessability values were 86.2% (262/304) and 92.1% (280/304) for MDCT and cine MRI, respectively. In assessable segments by both modalities (80.9%, 246/304), a significant correlation between MDCT and MRI was found (r = 0.89, 0.85, and 0.61, for EDWT, ESWT, and %SWT, respectively; all P < 0.05). Mean EDWT and ESWT values by MDCT were slightly lower than those by cine MRI (9.8 ± 3.6 vs. 10.0 ± 3.7 mm and 13.8 ± 4.4 vs. 14.1 ± 4.3 mm, respectively; both P < 0.01). Bland-Altman analysis revealed acceptable limits of agreement between MDCT and Cine MRI.

Conclusion

MDCT is a feasible method to assess regional LV wall thickness and systolic thickening.

Key words

Multislice computed tomography (CT) Magnetic resonance imaging (MRI) Left ventricular wall thickness Systolic thickening 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    White, HD, Norris, RM, Brown, MA, Brandt, PW, Whitlock, RM, Wild, CJ 1987Left ventricular end-systolic volume as the major determinant of survival after recovery from myocardial infarctionCirculation764451PubMedGoogle Scholar
  2. 2.
    Drozdz, J, Krzeminska-Pakula, M, Krecki, R, Dryja, P, Ciesielczyc, M, Lipiec, P,  et al. 2004Prognostic value of the parameters of the left ventricular systolic function in patients with heart failurePrzegl Lek616648PubMedGoogle Scholar
  3. 3.
    Ghali, JK, Liao, Y, Simmons, B, Castaner, A, Cao, G, Cooper, RS 1992The role of left ventricular hypertrophy in patients with or without coronary artery diseaseAnn Intern Med1178316PubMedGoogle Scholar
  4. 4.
    Rumberger, JA, Behrenbeck, T, Bell, MR, Breen, JF, Johnston, DL, Holmes, DR,Jr,  et al. 1997Determination of ventricular ejection fraction: a comparison of available imaging methods: the Cardiovascular Imaging Working GroupMayo Clin Proc7286070PubMedCrossRefGoogle Scholar
  5. 5.
    Cranney, GB, Lotan, CS, Dean, L, Baxley, W, Bouchard, A, Pohost, GM 1990Left ventricular volume measurement using cardiac axis nuclear magnetic resonance imaging: validation by calibrated ventricular angiographyCirculation8215463PubMedGoogle Scholar
  6. 6.
    Sakuma, H, Fujita, N, Foo, TK, Caputo, GR, Nelson, SJ, Hartiala, J,  et al. 1993Evaluation of left ventricular volume and mass with breath hold cine MR imagingRadiology18837780PubMedGoogle Scholar
  7. 7.
    Barkhausen, J, Goyen, M, Ruhm, SG, Eggebrecht, H, Debatin, JF, Ladd, ME 2002Assessment of ventricular function with single breath-hold real time steady-state free precession Cine MR imagingAJR Am J Roentgenol1787315PubMedGoogle Scholar
  8. 8.
    Haraikawa, T, Higashino, H, Sugawara, Y, Miki, H, Kurata, A, Higaki, J,  et al. 2006Assessment of left ventricular wall motion using 16-channel multislice computed tomography: comparison with left ventriculographyRadiat Med2415964PubMedCrossRefGoogle Scholar
  9. 9.
    Cerqueira, MD, Weissman, NJ, Dilsizian, V, Jacobs, AK, Kaul, S, Laskey, WK,  et al. 2002Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart: a statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart AssociationCirculation10553942PubMedCrossRefGoogle Scholar
  10. 10.
    Mochizuki T, Murase K, Fujiwara Y, Tanada S, Hamamoto K, Tauxe WN. Assessment of systolic thickening with thallium-201 ECG-gated single-photon emission computed tomography: a parameter for a local left ventricular function. J Nucl Med 32:1496–500Google Scholar
  11. 11.
    Bland, JM, Altman, DG 1986Statistical methods for assessing agreement between two methods of clinical measurementLancet130710PubMedGoogle Scholar
  12. 12.
    Boll, DT, Bossert, AS, Aschoff, AJ, Hoffmann, MH, Gilkeson, RC 2006Synergy of MDCT and cine MRI for the evaluation of cardiac motilityAJR Am J Roentgenol186S37986PubMedCrossRefGoogle Scholar
  13. 13.
    Belge, B, Coche, E, Pasquet, A, Vanoverschelde, JJ, Gerber, BL 2006Accurate estimation of global and regional cardiac function by retrospectively gated multidetector row computed tomography: comparison with cine magnetic resonance imagingEur Radiol16142433PubMedCrossRefGoogle Scholar
  14. 14.
    Tarakji, KG, Brunken, R, McCarthy, PM, Al-Chekakie, MO, Abdel-Latif, A, Pothier, CE,  et al. 2006Myocardial viability testing and effect of early intervention in patients with advanced left ventricular systolic dysfunctionCirculation1132307PubMedCrossRefGoogle Scholar
  15. 15.
    Elliott, PM, Poloniecki, J, Dickie, S, Sharma, S, Monserrat, L, Varnava, A,  et al. 2000Sudden death in hypertrophic cardiomyopathy: identification of risk patientsJ Am Coll Cardiol3622128PubMedCrossRefGoogle Scholar
  16. 16.
    Spirito, P, Bellone, P, Harris, KM, Bernabo, P, Bruzzi, P, Maron, BJ 2000Magnitude of left ventricular hypertrophy and risk of sudden death in hypertrophic cardiomyopathyN Engl J Med342177885PubMedCrossRefGoogle Scholar
  17. 17.
    Flohr, TG, McCollough, CH, Bruder, H, Petersilka, M, Gruber, K, Suss, C,  et al. 2006First performance evaluation of a dual-source CT (DSCT) systemEur Radiol1625668PubMedCrossRefGoogle Scholar
  18. 18.
    Kondo, C, Mori, S, Endo, M, Kusakabe, K, Suzuki, N, Hattori, A,  et al. 2005Real-time volumetric imaging of human heart without electrocardiographic gating by 256-detector row computed tomography: initial experienceJ Comput Assist Tomogr296948PubMedCrossRefGoogle Scholar

Copyright information

© Japan Radiological Society 2007

Authors and Affiliations

  • Rene E. Kanza
    • 1
  • Hiroshi Higashino
    • 1
  • Teruhito Kido
    • 1
  • Akira Kurata
    • 2
  • Makoto Saito
    • 2
  • Yoshifumi Sugawara
    • 1
  • Teruhito Mochizuki
    • 1
    Email author
  1. 1.Department of RadiologyEhime University Postgraduate School of MedicineShitsukawaJapan
  2. 2.Department of CardiologyEhime University Postgraduate School of MedicineShitsukawaJapan

Personalised recommendations