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Radiation Medicine

, Volume 25, Issue 3, pp 130–134 | Cite as

Usefulness of FDG PET for diagnosis and radiotherapy of the patient with malignant lymphoma involving bone marrow

  • Takashi NihashiEmail author
  • Kazumasa Hayasaka
  • Toshihide Itou
  • Takashi Sobajima
  • Rikio Kato
  • Kengo Ito
  • Yoshiyuki Ito
  • Takeo Ishigaki
  • Shinji Naganawa
CASE REPORT

Abstract

We experienced a case of relapsed malignant lymphoma with multiple bone marrow or bone lesions. The case was diagnosed as follicular lymphoma by cytological biopsy of the right iliac bone, with 67Ga scintigraphy showing abnormal, intense uptake in multiple bones. After about 10 months of systemic chemotherapy, a relapse was suspected because of pain in the bilateral legs and a high level of lactate dehydrogenase. Assessment of the lesions in the patient was difficult by computed tomography because the affected sites were localized mainly in the bone marrow. 18F-Fluorodeoxyglucose (FDG) positron emission tomography (PET) was useful for detecting accurately the relapse sites in the bone marrow and enabled us to determine the field for radiotherapy. There are only a few reports of FDG-PET findings for such bone marrow malignant lymphomas. Therefore, we report the findings of FDG-PET for this case and review some of the literature about bone marrow lymphomas.

Key words

Bone marrow Radiotherapy FDG-PET Follicular lymphoma 

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Copyright information

© Japan Radiological Society 2007

Authors and Affiliations

  • Takashi Nihashi
    • 1
    Email author
  • Kazumasa Hayasaka
    • 1
  • Toshihide Itou
    • 2
  • Takashi Sobajima
    • 1
  • Rikio Kato
    • 1
  • Kengo Ito
    • 3
  • Yoshiyuki Ito
    • 4
  • Takeo Ishigaki
    • 4
  • Shinji Naganawa
    • 4
  1. 1.Department of RadiologyNational Center for Geriatrics and GerontologyOhbuJapan
  2. 2.Department of HematologyNational Center for Geriatrics and GerontologyOhbuJapan
  3. 3.Department of Brain Science and Molecular ImagingNational Institute for Longevity SciencesAichiJapan
  4. 4.Department of RadiologyNagoya University Graduate School of MedicineNagoyaJapan

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