We evaluated the arteriovenous contrast on the source images of intracranial three-dimensional computed tomography (CT) angiography (3D-CTA) using a high-concentration (370 mg I/ml) contrast agent in comparison with intermediate-concentration (300 mg I/ml) contrast.
Materials and methods
With a fixed intravenous injection rate and scanning delay, 3D-CTA was performed using a single-detector helical CT scanner in 30 consecutive patients. We used 100 ml of iohexol 300 for 10 patients, 100 ml of iopamidol 300 for 10 patients, and 80 ml of iopamidol 370 for 10 patients. Attenuation values of the bilateral internal carotid arteries, bilateral middle cerebral arteries, basilar artery trunk, bilateral cavernous sinuses, bilateral basal veins, and Galenic vein were measured quantitatively on the axial CT angiographic source images.
High-concentration contrast significantly increased the attenuation values of the intracranial arterial system without increasing the attenuation of the venous system.
High-concentration contrast is helpful for obtaining valuable arteriovenous contrast on source images with intracranial 3D-CTA.
Contrast medium Cerebral vessels Computed tomographic angiography
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Kuszyk, BS, Normand, NJ, Fishman, EK 1998Neurovascular applications of CT angiographySemin Ultrasound CT MR19394404PubMedCrossRefGoogle Scholar
Vieco, PT, Shuman, WP, Alsofrom, GF, Gross, CE 1995Detection of circle of Willis aneurysms in patients with acute subarachnoid hemorrhage: a comparison of CT angiography and digital subtraction angiographyAJR Am J Roentgenol16542530PubMedGoogle Scholar
Liang, EY, Chan, M, Hsiang, JH, Walkden, SB, Poon, WS, Lam, WWM, et al. 1995Detection and assessment of intracranial aneurysms: value of CT angiography with shaded-surface displayAJR Am J Roentgenol1651497502PubMedGoogle Scholar
Katz, DA, Marks, MP, Napel, SA, Bracci, PM, Roberts, SL 1995Circle of Willis: evaluation with spiral CT angiography, MR angiography and conventional angiographyRadiology1954459PubMedGoogle Scholar
Alberico, RA, Patel, M, Casey, S, Jacobs, B, Maguire, W, Decker, R 1995Evaluation of the circle of Willis with three-dimensional CT angiography in patients with suspected intracranial aneurysmsAJNR Am J Neuroradiol1615718PubMedGoogle Scholar
Gorzer, H, Heimberger, K, Schindler, E 1994Spiral CT angiography with digital subtraction of extra- and intracranial vesselsJ Comput Assist Tomogr1883941PubMedCrossRefGoogle Scholar
Hsiang, JNK, Liang, EY, Lam, JMK, Zhu, XL, Poon, WS 1996The role of computed tomographic angiography in the diagnosis of intracranial aneurysms and emergent aneurysm clippingNeurosurgery384817PubMedCrossRefGoogle Scholar
Harrison, MJ, Johnson, BA, Gardner, GM, Welling, BG 1997Preliminary results on the management of unruptured intracranial aneurysms with magnetic resonance angiography and computed tomographic angiographyNeurosurgery4094755PubMedCrossRefGoogle Scholar
Zouaoui, A, Sahel, M, Marro, B, Clemenceau, S, Dargent, N, Bitar, A, et al. 1997Three-dimensional computed tomographic angiography in detection of cerebral aneurysms in acute subarachnoid hemorrhageNeurosurgery4112530PubMedCrossRefGoogle Scholar
Knauth, M, Kummer, RV, Jansen, O, Hahnel, S, Dorfler, A, Sartor, K 1997Potential of CT angiography in acute ischemic strokeAJNR Am J Neuroradiol18100110PubMedGoogle Scholar
Shrier, DA, Tanaka, H, Numaguchi, Y, Konno, S, Patel, U, Shibata, D 1997CT angiography in the evaluation of acute strokeAJNR Am J Neuroradiol18101120PubMedGoogle Scholar
Korogi, Y, Takahashi, M, Katada, K, Ogura, Y, Hasuo, K, Ochi, M, et al. 1999Intracranial aneurysms: detection with three dimensional CT angiography with volume rendering—comparison with conventional angiographic and surgical findingsRadiology1954459Google Scholar
Kato, Y, Sano, H, Katada, K, Ogura, Y, Hayakawa, M, Kanaoka, N, et al. 1999Application of three dimensional CT angiography to cerebral aneurysmsSurg Neurol5211321PubMedCrossRefGoogle Scholar
Villablanca, JP, Martin, N, Jahan, R, Gobin, YP, Frazee, J, Duckwiler, G, et al. 2000Volume-rendered helical computerized tomography angiography in the detection and characterization of intracranial aneurysmsJ Neurosurg9325464PubMedCrossRefGoogle Scholar
Doyon, D, Ducot, B, Halimi, PH, Spira, A, Noviant, A, Jacolot, A, et al. 1987Comparative trial of Hexabrix (320 mg iodine/ml), iohexol (300 mg iodine/ml) and Iopamiron (300 mg iodine/ml) in cerebral and spinal angiography: a preliminary reportBr J Radiol606715PubMedCrossRefGoogle Scholar
Schoellnast, H, Brader, P, Oberdabernig, B, Pisail, B, Deutschmann, HA, Fritz, GA, et al. 2005High-concentration contrast media in multiphasic abdominal multidetector-row computed tomography: effect of increased iodine flow rate on parenchymal and vascular enhancementJ Comput Assist Tomogr295827PubMedCrossRefGoogle Scholar
Loubeyre, P, Debard, I, Nemoz, C, Minh, VA 2000Using thoracic helical CT to assess iodine concentration in a small volume of nonionic contrast medium during vascular opacification: a prospective studyAJR Am J Roentgenol1747837PubMedGoogle Scholar
Cademartiri, F, Monye, CD, Pugliese, F, Mollet, NR, Runza, G, Lugt, AVD, et al. 2006High iodine concentration contrast material for noninvasive multislice computed tomography coronary angiography: iopromide 370 versus iomeprol 400Invest Radiol4134953PubMedCrossRefGoogle Scholar
Cademartiri, F, Mollet, NR, Lugt, AVD, McFadden, EP, Stijnen, T, Feyter, PJD, et al. 2005Intravenous contrast material administration at helical 16-detector row CT coronary angiography: effect of iodine concentration on vascular attenuationRadiology2366615PubMedCrossRefGoogle Scholar
Schoellnast, H, Deutschmann, HA, Fritz, GA, Stessel, U, Schaffler, GJ, Tillich, M 2005MDCT angiography of the pulmonary arteries: influence of iodine flow concentration on vessel attenuation and visualizationAJR Am J Roentgenol18419359PubMedGoogle Scholar