Summary
Metarhizosides A–G (1–7), seven new polysubstituted phenyl glucosides, were isolated from the extracts of solid rice medium of a marine-derived fungus Metarrhizium anisopliae. Compounds 1–7 all contain a polysubstituted phenyl group and the sugar unit is identified as 4′-O-methyl-β-D-glucopyranose. Their structures were elucidated by NMR spectroscopy and chemical method. These compounds were evaluated for anti-inflammatory activity by using LPS-stimulated murine macrophage RAW 264.7 cells and the cytotoxicities against four human cancer cell lines.
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17 July 2020
The article ���Polysubstituted Phenyl Glucosides Produced by the Fungus Metarrhizium anisopliae���, written by Wen-jing WANG, Chong DAI, Jian-ping WANG, Hu-cheng ZHU, Chun-mei CHEN, Yong-hui ZHANG, was originally published electronically on the publisher���s internet portal on May 2020 without open access. With the author(s)��� decision to opt for Open Choice, the copyright of the article is changed to �� The Author(s) 2020 and the article is forthwith distributed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made..
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The original version of this article was revised due to a retrospective Open Access order.
This work was financially supported by the Program for Changjiang Scholars of Ministry of Education of the People’s Republic of China (No. T2016088), the National Natural Science Foundation for Distinguished Young Scholars (No. 81725021), the National Natural Science Foundation of China (No. 31900288), the Program from the China Postdoctoral Science Foundation (No. 2019M652660), and the Integrated Innovative Team for Major Human Diseases Program of Tongji Medical College (HUST, China).
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Wang, Wj., Dai, C., Wang, Jp. et al. Polysubstituted Phenyl Glucosides Produced by the Fungus Metarrhizium anisopliae. CURR MED SCI 40, 232–238 (2020). https://doi.org/10.1007/s11596-020-2168-2
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DOI: https://doi.org/10.1007/s11596-020-2168-2