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Epstein-Barr Virus EA-IgA, VCA-IgA, and EBVNA-IgG Antibodies in a Population of Wuhan, China

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Summary

The study investigated the distribution of Epstein-Barr virus (EBV) EA-IgA, VCA-IgA, and EBVNA-IgG antibodies in a local population of Wuhan, China. Chemiluminescence immunoassay (CLIA) was used to detect EBV EA-IgA, VCA-IgA, and EBVNA-IgG antibodies in 972 subjects undergoing physical examination in Wuhan, and the results were analyzed. The detection rate of EBV was positively correlated with age. In the 972 cases, there was significant difference between different genders in the positive rate of VCA-IgA and EBVNA-IgG. Moreover, the positive rate of VCA-IgA and EBVNA-IgG was higher in men ≥ 60 years old than in those < 60 but no significant differences were found in three antibodies among various age groups. Our results suggested that the EBV infection should be intensively monitored in elderly people in Wuhan.

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Acknowledgments

The authors would like to thank Mei-hong ZENG and Yan SHEN of the Physical Examination Center, Union Hospital for their help with participant recruitment, and Liqin ZHU of the Physical Examination Center, Union Hospital for her assistance in laboratory management.

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Author notes

  1. These authors contributed equally to this work.

Authors and Affiliations

  1. Department of Otolaryngology, Huazhong University of Science and Technology, Wuhan, 430022, China

    Zhen-gang Tang, Yun-cheng Li & Wei-jia Kong

  2. Physical Examination Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China

    Hui-hui Li, Xin Xu, Jun-chao Zeng & Rui Yang

  3. School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China

    Mei-xia Lv

Authors
  1. Zhen-gang Tang
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  2. Hui-hui Li
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  3. Yun-cheng Li
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  4. Mei-xia Lv
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  5. Xin Xu
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  6. Jun-chao Zeng
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  7. Wei-jia Kong
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  8. Rui Yang
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Corresponding authors

Correspondence to Wei-jia Kong or Rui Yang.

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Conflict of Interest Statement

The authors declare that there is no conflict of interest with any financial organization or corporation or individual that can inappropriately influence this work.

This project was supported by grants from the Natural Science Foundation of Hubei Province (No. 2018CFB749 and No. 2018ADC073), the Scientific Research Fund of Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (No. 02.03.2017-292 and No. 02.03.2017-327) and General Project of Hubei Health Committee (No. 02.07.19030018).

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Tang, Zg., Li, Hh., Li, Yc. et al. Epstein-Barr Virus EA-IgA, VCA-IgA, and EBVNA-IgG Antibodies in a Population of Wuhan, China. CURR MED SCI 40, 168–171 (2020). https://doi.org/10.1007/s11596-020-2160-x

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  • DOI: https://doi.org/10.1007/s11596-020-2160-x

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