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Influence of Acupuncture on Autonomic Balance in Adult Tinnitus Patients: An Exploratory Study

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Summary

Acupuncture is an alternative therapy for tinnitus in clinical practice. The mechanism by which acupuncture can alleviate tinnitus is still unknown. Autonomic nervous system was reported to be responsible for tinnitus. The aim of this study was to explore the effect of acupuncture on autonomic balance in adult tinnitus patients. Thirty patients were randomly assigned into either the deep acupuncture (DA) group or the shallow acupuncture (SA) group. Each patient received 6 acupuncture sessions (a–f phase) over three weeks. Measures of heart rate variability and Tinnitus Handicap Inventory (THI) were obtained at baseline and after the sixth acupuncture session in all patients. The results showed that the low frequency/high frequency (LF/HF) pattern was increased at b–f phase until the sixth acupuncture session when compared with that at the first acupuncture session in DA group. However, it continuously increased at b–f phase in SA group even at the sixth acupuncture session, which was not significantly different from that at the first acupuncture session. The decrease in THI in DA group was greater than that in SA group after 3-week treatment (P=0.043). Our preliminary study suggests three-week deep acupuncture can improve tinnitus symptoms in adult tinnitus patients, which may be related to the regulation of autonomic nervous system balance.

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References

  1. Tunkel DE, Bauer CA, Sun GH, et al. Clinical practice guideline: tinnitus. Otolaryngol Head Neck Surg, 2014,151(2 Suppl):S1–S40

    Article  Google Scholar 

  2. Park KH, Lee SH, Koo JW, et al. Prevalence and associated factors of tinnitus: data from the Korean National Health and Nutrition Examination Survey 2009–2011. J Epidemiol, 2014,24(5):417–426

    Article  Google Scholar 

  3. Kim HJ, Lee HJ, An SY, et al. Analysis of the prevalence and associated risk factors of tinnitus in adults. PLoS One, 2015,10(5):e0127578

    Article  Google Scholar 

  4. Yang H, Cai Y, Guo H, et al. Prevalence and factors associated with tinnitus: data from adult residents in Guangdong province, South of China. Int J Audiol, 2018,57(12):892–899

    Article  Google Scholar 

  5. Okada DM, Onishi ET, Chami FI, et al. Acupuncture for tinnitus immediate relief. Braz J Otorhinolaryngol, 2006,72:182–186

    Article  Google Scholar 

  6. Han BI, Lee HW, Kim TY, et al. Tinnitus: characteristics, causes, mechanisms, and treatments. J Clin Neurol, 2009,5(1):11–19

    Article  Google Scholar 

  7. Tyler R, Cacace A, Stocking C, et al. Vagus Nerve Stimulation Paired with Tones for the Treatment of Tinnitus: A Prospective Randomized Doubleblind Controlled Pilot Study in Humans. Sci Rep, 2017,7(1):11960

    Article  Google Scholar 

  8. Hyvärinen P, Yrttiaho S, Lehtimäki J, et al. Transcutaneous vagus nerve stimulation modulates tinnitus-related beta- and gamma-band activity. Ear Hear, 2015,36(3):e76–e85

    Article  Google Scholar 

  9. Jackson A, MacPherson H, Hahn S. Acupuncture for tinnitus: a series of six n = 1 controlled trials. Complement Ther Med, 2006,14:39–46

    Article  Google Scholar 

  10. Liu F, Han X, Li Y, et al. Acupuncture in the treatment of tinnitus: a systematic review and meta-analysis. Eur Arch Otorhinolaryngol, 2016,273(2):285–294

    Article  Google Scholar 

  11. Naderinabi B, Soltanipour S, Nemati S, et al. Acupuncture for chronic nonpulsatile tinnitus: A randomized clinical trial. Caspian J Intern Med, 2018,9(1):38–45

    PubMed  PubMed Central  Google Scholar 

  12. Doi MY, Tano SS, Schultz AR, et al. Effectiveness of acupuncture therapy as treatment for tinnitus: a randomized controlled trial. Braz J Otorhinolaryngol, 2016,82(4):458–465

    Article  Google Scholar 

  13. Kim BH, Kim K, Nam HJ. A comparative study on the effects of systemic manual acupuncture, periauricular electroacupuncture, and digital electroacupuncture to treat tinnitus: A randomized, paralleled, open-labeled exploratory trial. BMC Complement Altern Med, 2017,17(1):85

    Article  Google Scholar 

  14. Datzov E, Danev S, Haralanov H, et al. Tinnitus, heart rate variability, and some biochemical indicators. Int Tinnitus J, 1999,5:20–23

    CAS  PubMed  Google Scholar 

  15. Moon YK, Kim MH, Nam HJ et al. Comparison of the effectiveness between transcutaneous electrical nerve stimulation, manual acupuncture, and electroacupuncture on tinnitus: study protocol for a randomized controlled trial. Trials, 2018,19(1):342

    Article  Google Scholar 

  16. Shu Q, Wang H, Litscher D, et al. Acupuncture and Moxibustion have Different Effects on Fatigue by Regulating the Autonomic Nervous System: A Pilot Controlled Clinical Trial. Sci Rep, 2016,6:37846

    Article  CAS  Google Scholar 

  17. Noda Y, Izuno T, Tsuchiya Y, et al. Acupuncture-induced changes of vagal function in patients with depression: A preliminary sham-controlled study with press needles. Complement Ther Clin Pract, 2015,21:193–200

    Article  Google Scholar 

  18. Litscher G, Cheng WP, Cheng GY, et al. Acupuncture Point Laterality: Investigation of Acute Effects of Quchi (LI11) in Patients with Hypertension Using Heart Rate Variability. Evid Based Complement Alternat Med, 2014:979067

  19. Matsushima JI, Kamada T, Sakai N, et al. Increased Parasympathetic Nerve Tone in Tinnitus Patients Following Electrical Promontory Stimulation. Int Tinnitus J, 1996,2:67–71

    CAS  PubMed  Google Scholar 

  20. Li QQ, Shi GX, Fu XX, et al. Effects of deqi on autonomic balance in adult tinnitus patients: study design of a randomized controlled trial. Evid Based Complement Alternat Med, 2013,2013:756012

    PubMed  PubMed Central  Google Scholar 

  21. Wang HT, Li M, Liu P, et al. Guideline for the diagnosis and treatment of tinnitus. Zhonghua Er Ke Xue Za Zhi (Chinese), 2009,7(03):185

    Google Scholar 

  22. Litscher G, He W, Yi SH, et al. Heart rate variability and complementary medicine. Evid Based Complement Alternat Med, 2014:395485

  23. Shi X, Wang H, Wang L, et al. Can tongue acupuncture enhance body acupuncture? First results from heart rate variability and clinical scores in patients with depression. Evid Based Complement Alternat Med, 2014:329746

  24. Litscher G, Cheng G, Wang L, et al. Biomedical Teleacupuncture between China and Austria Using Heart Rate Variability-Part 2: Patients with Depression. Evid Based Complement Alternat Med, 2012,2012:145904

    PubMed  PubMed Central  Google Scholar 

  25. Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Eur Heart J, 1996,17:354–381

    Article  Google Scholar 

  26. Kam AC, Cheung AP, Chan PY, et al. Psychometric properties of the Chinese (Cantonese) Tinnitus Handicap Inventory. Clin Otolaryngol, 2009,34(4):309–315

    Article  CAS  Google Scholar 

  27. Chae Y, Kim SY, Park HS, et al. Experimentally manipulating perceptions regarding acupuncture elicits different responses to the identical acupuncture stimulation. Physiol Behav, 2008,95:515–520

    Article  CAS  Google Scholar 

  28. Kim JI, Choi JY, Lee DH, et al. Acupuncture for the treatment of tinnitus: a systematic review of randomized clinical trials. BMC Complement Altern Med, 2012,12:97

    Article  Google Scholar 

  29. Vanneste S, Azevedo A, De Ridder D. The effect of naltrexone on the perception and distress in tinnitus: an open-label pilot study. Int J Clin Pharmacol Ther, 2013,51(1):5–11

    Article  CAS  Google Scholar 

  30. Jeon SW, Kim KS, Nam HJ. Long-term effect of acupuncture for treatment of tinnitus: a randomized, patient- and assessor-blind, sham-acupuncture-controlled, pilot trial. J Altern Complement Med, 2012,18:693–699

    Article  Google Scholar 

  31. Choi EJ, Yun Y, Yoo S, et al. Autonomic conditions in tinnitus and implications for korean medicine. Evid Based Complement Alternat Med, 2013,2013:402585

    PubMed  PubMed Central  Google Scholar 

  32. Bolea J, Pueyo E, Orini M, et al. Influence of Heart Rate in Non-linear HRV Indices as a Sampling Rate Effect Evaluated on Supine and Standing. Front Physiol, 2016,7:501

    Article  Google Scholar 

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Acknowledgments

The authors thank all the patients who participated in the study.

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Authors and Affiliations

  1. School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, 100029, China

    Jian-feng Tu, Mirim Kim, Jing-wen Yang, Gerhard Litscher & Cun-zhi Liu

  2. Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing, 100010, China

    Qian-qian Li & Guang-xia Shi

  3. Research Unit for Complementary and Integrative Laser Medicine, Research Unit of Biomedical Engineering in Anesthesia and Intensive Care Medicine and TCM Research Center Graz, Medical University of Graz, Graz, 8036, Austria

    Gerhard Litscher, Lu Wang & Daniela Litscher

Authors
  1. Jian-feng Tu
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  2. Mirim Kim
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  3. Jing-wen Yang
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  4. Qian-qian Li
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  5. Gerhard Litscher
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  6. Lu Wang
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  7. Guang-xia Shi
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  8. Daniela Litscher
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  9. Cun-zhi Liu
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Corresponding authors

Correspondence to Gerhard Litscher or Cun-zhi Liu.

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Conflict of Interest Statement

The authors have no conflict of interest.

This study was supported by grants from Beijing Health System (China)-Hight Level Health Technology Talent Cultivation Plan (No. 2011-03-055) and Austrian Federal Ministry of Education, Science and Research [Sino-Austrian TCM Research on Lifestyle-related Diseases: Innovative Acupuncture (2016-2019)].

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Tu, Jf., Kim, M., Yang, Jw. et al. Influence of Acupuncture on Autonomic Balance in Adult Tinnitus Patients: An Exploratory Study. CURR MED SCI 39, 947–953 (2019). https://doi.org/10.1007/s11596-019-2127-y

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  • DOI: https://doi.org/10.1007/s11596-019-2127-y

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