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Initial CT-guided percutaneous biopsy of vertebral lesions: Evaluation of its diagnostic accuracy and clinical value

Journal of Huazhong University of Science and Technology [Medical Sciences] volume 35, pages 569–573 (2015)Cite this article

Summary

This study aimed to examine the diagnostic accuracy and clinical efficacy of initial CT-guided percutaneous biopsy of the vertebral lesions. A total of 305 percutaneous biopsies of the vertebral lesions were performed under either CT guidance (n=127) or C-arm guidance (n=178). The diagnostic accuracy rate was evaluated by comparing the histopathological diagnosis with the ultimate diagnosis. The histopathological diagnosis was consistent with the ultimate diagnosis in 108 (85.0%, 108/127) cases of CT-guided biopsy and in 135 (75.8%, 135/178) cases of C-arm guided biopsy and there was a significant difference. The accuracy of diagnosis based on biopsies varied with different diseases, including primary benign or malignant tumors, metastatic tumors, inflammatory lesions and fractures. A second biopsy or further examinations were required for patients with negative result obtained in the initial biopsy. The complication rate was 3.1% (4/127) in CT-guided biopsy and 7.3% (13/178) in C-arm guided biopsy. In conclusion, CT-guided percutaneous biopsy is an accurate and safe technique for biopsy of the vertebral lesions.

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Affiliations

  1. Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China

    Wen-bin Hua, Qiang Wu, Bo Zhang, Shu-hua Yang, Zeng-wu Shao, Wei-hua Xu & Xu-dong Zhang

  2. Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China

    Ye Wang

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  1. Wen-bin Hua
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  2. Qiang Wu
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  3. Bo Zhang
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  4. Shu-hua Yang
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  5. Zeng-wu Shao
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  6. Wei-hua Xu
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  7. Ye Wang
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  8. Xu-dong Zhang
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Correspondence to Qiang Wu.

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Hua, Wb., Wu, Q., Zhang, B. et al. Initial CT-guided percutaneous biopsy of vertebral lesions: Evaluation of its diagnostic accuracy and clinical value. J. Huazhong Univ. Sci. Technol. [Med. Sci.] 35, 569–573 (2015). https://doi.org/10.1007/s11596-015-1472-8

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  • DOI: https://doi.org/10.1007/s11596-015-1472-8

Key words

  • computed tomography
  • biopsy
  • spine
  • diagnosis