Summary
The purpose of this study was to evaluate the value of multi-detector computed tomography (MDCT) angiography for the diagnosis of congenital aortic arch anomalies and present the radiological images of congenital aortic arch anomalies in Chinese children. MDCT angiography and transthoracic echocardiography (TTE) were applied for the diagnosis of congenital aortic arch anomalies in 362 Chinese children between May 2006 and December 2011 (age ranges from 5 days to 12 years; mean age, 3.3 years). Surgery and/or catheter angiography (CA) were conducted in all patients to confirm the final diagnosis. In the 362 Chinese children with congenital heart anomalies, congenital aortic arch anomalies were definitely diagnosed in 198 children and 164 children ruled out by operation and/or (CA). Among the 198 children with anomalies, coarctation of aorta (CoA), interruption of aortic arch (IAA), right aortic arch, aberrant right subclavian artery and double aortic arch were diagnosed in 134, 32, 20, 10 and 2 children respectively, and there were 6 cases with uncommon congenital aortic arch anomalies: 2 had double aortic arch including 1 with five branches of the aortic arch, 2 had isolation of the right subclavian artery with two patent ductus arteriosus (PDA), 1 had an isolation of the common carotid artery with a PDA, and 1 had double PDA with a single ventricle and pulmonary artery atresia. Among the 32 children with IAA, 28 were of type A, and 4 were of type B. The diagnostic sensitivity, specificity and accuracy of MDCT angiography for congenital aortic arch anomalies were 100% (198/198), 98% (161/164) and 99% (359/362), respectively. The diagnostic sensitivity, specificity and accuracy of TTE were 92% (182/198), 81% (133/164) and 87% (315/362), respectively. In conclusion, MDCT angiography is a reliable, noninvasive imaging technique for the diagnosis of congenital aortic arch anomalies in children. Sometimes, even more information can be obtained from this technique than from conventional angiography.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Ikeda T, Ban T. Congenital anomalies of the aortic arch. Ryoikibetsu Shokogun Shirizu (Japanese), 1996(13):199–202
Dillman JR, Attili AK, Agarwal PP, et al. Common and uncommon vascular rings and slings: a multi-modality review. Pediatr Radiol, 2011,41(11):1440–1454; quiz 1489–1490
Vucurevic G, Tanaskovic S, Ilijevski N, et al. Right-sided aortic arch with anomalous origin of the left subclavian artery: case report. Srp Arh Celok Lek (Serbian), 2011, 139(9–10):666–668
Lee EY, Siegel MJ, Hildebolt CF, et al. MDCT evaluation of thoracic aortic anomalies in pediatric patients and young adults: comparison of axial, multiplanar, and 3D images. AJR Am J Roentgenol, 2004,182(3):777–784
Ming Z, Yumin Z, Yuhua L, et al. Diagnosis of congenital obstructive aortic arch anomalies in Chinese children by contrast-enhanced magnetic resonance angiography. J Cardiovasc Magn Reson, 2006,8(5):747–753
Kimura-Hayama ET, Melendez G, Mendizabal AL, et al. Uncommon congenital and acquired aortic diseases: role of multidetector CT angiography. Radiographics, 2010,30(1):79–98.
Ramos-Duran L, Nance JW Jr, Schoepf UJ, et al. Developmental aortic arch anomalies in infants and children assessed with CT angiography. AJR Am J Roentgenol, 2012,198(5):466–474
Spevak PJ, Johnson PT, Fishman EK. Surgically corrected congenital heart disease: utility of 64-MDCT. AJR Am J Roentgenol, 2008,191(3):854–861
Bean M J, Pannu H, Fishman EK. Three-dimensional computed tomographic imaging of complex congenital cardiovascular abnormalities. J Comput Assist Tomogr, 2005,29(6):721–724.
Stuhlfaut JW, Barest G, Sakai O, et al. Impact of MDCT angiography on the use of catheter angiography for the assessment of cervical arterial injury after blunt or penetrating trauma. AJR Am J Roentgenol, 2005,185(4):1063–1068
Onbas O, Kantarci M, Koplay M, et al. Congenital anomalies of the aorta and vena cava: 16-detector-row CT imaging findings. Diagn Interv Radiol, 2008,14(3): 163–171
Ou P, Celermajer DS, Calcagni G, et al. Three-dimensional CT scanning: a new diagnostic modality in congenital heart disease. Heart, 2007,93(8):908–913
Khatri S, Varma SK, Khatri P, et al. 64-slice multidetector-row computed tomographic angiography for evaluating congenital heart disease. Pediatr Cardiol, 2008,29(4): 755–762
Choi HS, Shin DH, Kim KR, et al. Preoperative three-dimensional CT angiography to distinguish between an aberrant subclavian artery and a double aortic arch in thyroid surgery: Report of 2 cases. Auris Nasus Larynx, 2011,38(1):127–132
Herzog C, Mulvihill D M, Nguyen S A, et al. Pediatric cardiovascular CT angiography: radiation dose reduction using automatic anatomic tube current modulation. AJR Am J Roentgenol, 2008,190(5):1232–1240
Jonas RA, Quaegebeur JM, Kirklin JW, et al. Outcomes in patients with interrupted aortic arch and ventricular septal defect. J Thorac Cardiovasc Surg, 1994,107(4): 1099–1113
Zapata H, Edwards J E, Titus J L. Aberrant right subclavian artery with left aortic arch: associated cardiac anomalies. Pediatr Cardiol, 1993,14(3):159–161
Zhu M, Zhong YM, Jin B, et al. Congenital aortic arch anomalies: diagnosis using contrast enhancement magnetic resonance angiography. BME & Clin Med, 2006,10(5): 296–299
Author information
Authors and Affiliations
Corresponding author
Additional information
This project was supported by the Natural Science Foundation of Hubei Province (No. 2012FFB04422).
Rights and permissions
About this article
Cite this article
Chen, X., Qu, Yj., Peng, Zy. et al. Diagnosis of congenital aortic arch anomalies in chinese children by multi-detector computed tomography angiography. J. Huazhong Univ. Sci. Technol. [Med. Sci.] 33, 447–451 (2013). https://doi.org/10.1007/s11596-013-1140-9
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11596-013-1140-9