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Assessment of left atrial function in diabetes mellitus by left atrial volume tracking method

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Summary

The value of the left atrial volume tracking (LAVT) method in the evaluation of left atrial (LA) function in patients with diabetes mellitus (DM) was examined in this study. Fifty-eight DM patients as DM group and 40 healthy people as normal control group were enrolled in this study. EUB-6500 echocardiographic imaging system with LAVT was applied to display and analyze the LA volume curve imaging on LV apical two and four chamber views. The maximal LA volume at end-systole (LAVmax), LA volume at the onset of ECG-P wave (LAVp), the minimal LA volume at end-diastole (LAVmin) from the LA volume curve were acquired and recorded. All values above were standardized by body surface area (BSA). Then the passive, active and total LA volume (LAVIpass, LAVIact, LAVItotal) and empting rate (%LAVIpass, %LAVIact, %LAVItotal), effective passive and active empting rate (%eLAVIpass, %eLAVIact), and the proportionality of passive empting volume and active empting volume were calculated. The LAVIp, LAVIact, LAVItotal, %LAVIact, %LAVItotal and %eLAVIact were significantly higher in the DM group than those in the control group, whereas the LAVIpass, %LAVIpass, %eLAVIpass and LAVIpass/act were lower (all P<0.05). For the LA volume change in DM, the active empting volume was enhanced at end-diastole. It was concluded that LAVT is a potentially useful tool to evaluate the function of LA.

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References

  1. Leung DY, Boyd A, Ng AA, et al. Echocardiographic evaluation of left atrial size and function: current understanding, pathophysiologic correlates, and prognostic implications. Am Heart J, 2008,156(6):1056–1064

    Article  PubMed  Google Scholar 

  2. Freire CM, Moura AL, Barbosa Mde M, et al. Left ventricle diastolic dysfunction in diabetes: an update. Arq Bras Endocrinol Metabol, 2007,51(2):168–175

    PubMed  Google Scholar 

  3. Lim TK, Ashrafian H, Dwivedi G, et al. Increased left atrial volume index is an independent predictor of raised serum natriuretic peptide in patients with suspected heart failure but normal left ventricular ejection fraction: Implication for diagnosis of diastolic heart failure. Eur J Heart Fail, 2006,8(1):38–45

    Article  CAS  PubMed  Google Scholar 

  4. de Simone GD, Grenco R, Mureddu G, et al. Relation of left ventricular diastolic properties to systolic in arterial hypertension. Circulation, 2000,101(2):152–153

    PubMed  Google Scholar 

  5. Stoddard MF, Labovitz AJ, Pearson AC. The role of Doppler echocardiography in the assessment of left ventricular diastolic function. Echocardiography, 1992,9(4):387–406

    Article  CAS  PubMed  Google Scholar 

  6. Cioffi G, Chinali M, Mureddu GF, et al. Left atrial systolic force: comparison between two methods for the noninvasive assessment of left atrial systolic function. J Cardiovasc Med, 2008,9(6):601–607

    Article  Google Scholar 

  7. Muscholl M, Dennig K, Kraus F, et al. Echocardiographic and Doppler echocardiographic characterization of left ventricular diastolic function. Herz, 1990,15(6):377–392

    CAS  PubMed  Google Scholar 

  8. Kurokawa S, Okuri H, Sasaoka T, et al. Doppler echocardiographic method to determine early and late diastolic filling volume separately. Validation and relationship between filling velocity and volume. Jpn Heart J, 1998,39(4):489–501

    CAS  Google Scholar 

  9. Cuspidi C, Meani S, Fusi V, et al. Prevalence and correlates of left atrial enlargement in essential hypertension: role of ventricular geometry and the metabolic syndrome: the evaluation of target organ damage in hypertension study. J Hypertens, 2005, 23(4):875–882

    Article  CAS  PubMed  Google Scholar 

  10. Rossi A, Zardini P, Marino P. Modulation of left atrial function by ventricular filling impairment. Heart Fail Rev, 2000,5(4):325–331

    Article  CAS  PubMed  Google Scholar 

  11. Spencer KT, Mor-Avi V, Kirkpatrick J, et al. Normal values of left ventricular systolic and diastolic function derived from signal-averaged acoustic quantification waveforms: a multicenter study. J Am Soc Echocardiogr, 2003,16(12):1244–1251

    Article  PubMed  Google Scholar 

  12. Yamaguchi H, Yoshida J, Yamamoto K, et al. Elevation of plasma brain natriuretic peptide is a hallmark of diastolic heart failure independent of ventricular hypertrophy. J Am Coll Cardiol, 2004,43(1):55–60

    Article  CAS  PubMed  Google Scholar 

  13. Mureddu GF, Cioffi G, Stefenelli C, et al. Relationships of the appropriateness of left ventricular mass to left atrial size and function in arterial hypertension. J Cardiovasc Med, 2007,8(6):445–452

    Article  Google Scholar 

  14. Muranaka A, Yuda S, Tsuchihashi K, et al. Quantitative assessment of left ventricular and left atrial functions by strain rate imaging in diabetic patients with and without hypertension. Echocardiography, 2009,26(3): 262–271

    Article  PubMed  Google Scholar 

  15. Tsang TS, Barnes ME, Gersh BJ, et al. Left atrial volume as a morphophysiologic expression of left ventricular diastolic dysfunction and relation to cardiovascular risk burden. Am J Cardiol, 2002,90(12):1284–1289

    Article  PubMed  Google Scholar 

  16. Wakami K, Ohte N, Asada K, et al. Correlation between left ventricular end-diastolic pressure and peak left atrial wall strain during left ventricular systole. J Am Soc Echocardiogr, 2009,22(7):847–851

    Article  PubMed  Google Scholar 

  17. Stöllberger C. Transthoracic and transesophageal echocardiography in atrial fibrillation. J Thromb Thrombolysis, 1999,7(1):73–77

    Article  PubMed  Google Scholar 

  18. Okamatsu K, Takeuchi M, Nakai H, et al. Effects of aging on left atrial function assessed by two-dimensional speckle tracking echocardiography. J Am Soc Echocardiogr, 2009,22(1):70–75

    Article  PubMed  Google Scholar 

  19. Ogawa K, Hozumi T, Sugioka K, et al. Automated assessment of left atrial function from time-left atrial volume curves using a novel speckle tracking imaging method. J Am Soc Echocardiogr, 2009,22(1):63–69

    Article  PubMed  Google Scholar 

  20. D’Andrea A, Caso P, Romano S, et al. Association between left atrial myocardial function and exercise capacity in patients with either idiopathic or ischemic dilated cardiomyopathy: a two-dimensional speckle strain study. Int J Cardiol, 2009,132(3):354–363

    Article  PubMed  Google Scholar 

  21. Cho IJ, Pyun WB, Shin GJ. The influence of the left ventricular geometry on the left atrial size and left ventricular filling pressure in hypertensive patients, as assessed by echocardiography. Korean Circ J, 2009,39(4):145–150

    Article  PubMed  Google Scholar 

  22. Abhayaratna WP, Seward JB, Appleton CP, et al. Left atrial size: physiologic determinants and clinical applications. J Am Coll Cardiol, 2006,47(12): 2357–2363

    Article  PubMed  Google Scholar 

  23. Hoit BD. Assessing atrial mechanical remodeling and its consequences. Circulation, 2005,112(3):304–306

    Article  PubMed  Google Scholar 

  24. Murata M, Iwanaga S, Tamura Y, et al. A real-time three-dimensional echocardiographic quantitative analysis of left atrial function in left ventricular diastolic dysfunction. Am J Cardiol, 2008,102(8):1097–1102

    Article  PubMed  Google Scholar 

  25. Cioffi G, Mureddu GF, Stefenelli C, et al. Relationship between left ventricular geometry and left atrial size and function in patients with systemic hypertension. J Hypertens, 2004,22(8):1589–1596

    Article  CAS  PubMed  Google Scholar 

  26. Kokubu N, Yuda S, Tsuchihashi K, et al. Relationship between left ventricular geometry and left atrial size and function in patients with systemic hypertension. Hypertens Res, 2007,30(8):13–21

    Article  PubMed  Google Scholar 

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Correspondence to Qing Lv  (吕 清).

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Both authors contributed equally to this work.

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Huang, G., Zhang, L., Xie, M. et al. Assessment of left atrial function in diabetes mellitus by left atrial volume tracking method. J. Huazhong Univ. Sci. Technol. [Med. Sci.] 30, 819–823 (2010). https://doi.org/10.1007/s11596-010-0665-4

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  • DOI: https://doi.org/10.1007/s11596-010-0665-4

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