Skip to main content
SpringerLink
Log in

Shigatoxin

Verursacher des hämolytisch-urämischen Syndroms (HUS) bei der durch enterohämorrhagische Eschericha coli (EHEC) verursachten Kolitis

  • Nephro molekular
  • Published:
Der Nephrologe Aims and scope

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. Sandvig K (2001) Shiga toxins. Toxicon 39(11):1629–1635

    Article  PubMed  CAS  Google Scholar 

  2. Takao T, Tanabe T, Hong YM et al (1988) Identity of molecular structure of Shiga-like toxin I (VT1) from Escherichia coli O157:H7 with that of Shiga toxin. Microb Pathog 5(5):57–69

    Article  PubMed  CAS  Google Scholar 

  3. Konowalchuk J, Speirs JI, Stavric S (1977) Vero response to a cytotoxin of Escherichia coli. Infect Immun 18(3):775–779

    PubMed  CAS  Google Scholar 

  4. Gyles CL (2007) Shiga toxin-producing Escherichia coli: an overview. J Anim Sci 85(13 Suppl):E45–E62

    Article  PubMed  CAS  Google Scholar 

  5. Zoja C, Buelli S, Morigi M (2010) Shiga toxin-associated hemolytic uremic syndrome: pathophysiology of endothelial dysfunction. Pediatr Nephrol 25(11):2231–2240

    Article  PubMed  Google Scholar 

  6. Moake J (2009) Thrombotic microangiopathies: multimers, metalloprotease, and beyond. Clin Transl Sci 2(5):366–373

    Article  PubMed  CAS  Google Scholar 

  7. Orth D, Khan AB, Naim A et al (2009) Shiga toxin activates complement and binds factor H: evidence for an active role of complement in hemolytic uremic syndrome. J Immunol 182(10):6394–6400

    Article  PubMed  CAS  Google Scholar 

  8. Stahl AL, Sartz L, Karpman D (2011) Complement activation on platelet-leukocyte complexes and microparticles in enterohemorrhagic Escherichia coli-induced hemolytic uremic syndrome. Blood 117(20):5503–5513

    Article  PubMed  Google Scholar 

  9. Lapeyraque AL, Malina M, Fremeaux-Bacchi V et al (2011) Complement blockade in severe Shiga-toxin-associated HUS. N Engl J Med [Epub ahead of print]

Download references

Interessenkonflikt

Der korrespondierende Autor weist auf folgende Beziehungen hin: Alexion, Novartis, Cellpharm, Fresenius, Roche, Otsuka.

Author information

Authors and Affiliations

  1. Klinik für Nephrologie, Universitätsklinikum Essen, Universität Duisburg-Essen, Hufelandstr. 55, 45122, Essen, Deutschland

    T. Feldkamp

  2. Klinik für Nephrologie, Helios-Kliniken Schwerin, Schwerin, Deutschland

    J. Nürnberger

Authors
  1. T. Feldkamp
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. Nürnberger
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to T. Feldkamp.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Feldkamp, T., Nürnberger, J. Shigatoxin. Nephrologe 6, 350–354 (2011). https://doi.org/10.1007/s11560-011-0557-z

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11560-011-0557-z

Search

Navigation