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Development and assessment of novel assist device for cardiac cannulation

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International Journal of Computer Assisted Radiology and Surgery Aims and scope Submit manuscript

Abstract

Purpose

Congenital heart defects are the most common birth defects in the USA and in 25% of cases need to be treated with cardiovascular interventions. One of such interventions is the postoperative use of an extracorporeal membrane oxygenation (ECMO) machine for the treatment of cardiorespiratory failure. The process of placing the patient on the ECMO is extremely time-critical and requires the use of cardiac cannulation. For the first time, our team developed and evaluated a new quick-connect cannulation system that allows for rapid, easy, and safe ECMO cannulation in the pediatric population. The design should eliminate the need for purse-string sutures that are currently used to secure cannulas, as the cannulas will be inserted through a port that is glued to the cardiovascular tissue.

Methods

The rapid cannulation assistance device was designed on the SolidWorks computer-aided design software using the dimensions of the commercially available arterial and venous catheters. These designs were then 3D printed, and tensile testing was performed. Then, a flow loop was developed, and cannulation was performed and analyzed on both 3D-printed hearts and porcine hearts.

Results

The rapid cannulation assistance device was designed and 3D printed. Tensile testing found that the parts were strong enough to withstand forces that may be introduced in studies. 3D-printed and porcine heart tests with a flow loop found no leakage with the 3D-printed hearts but minimal leaking with the porcine hearts. However, this leakage was observed at the junction between the device and the heart, leading us to believe that a glue better suited to attach the device to the heart would prevent leakage in the future.

Conclusions

This project successfully demonstrated how a rapid cannulation assistance device could be developed and tested. Future studies will be conducted that address device adhesion to the cardiovascular tissue so that accurate pressure and flow rates can be measured. Future studies will also include testing the device in a fluid environment to more effectively analyze the device success and comparing the time required to cannulate using our device compared to the standard of care.

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Funding

This project was funded by NIH R21HD105965.

Author information

Author notes

  1. Elizabeth Fischer and Mikias Gebremeskel contributed jointly to this work and should be considered co-first authors.

Authors and Affiliations

  1. Sheikh Zayed Institute for Pediatric Surgical Innovation, Children’s National Hospital, Washington, D.C., USA

    Elizabeth Fischer, Mikias Gebremeskel, Kochai Jan Jawed & Kevin Cleary

  2. Division of Cardiovascular Surgery, Children’s National Hospital, Washington, D.C., USA

    Mahmut Ozturk & Can Yerebakan

Authors
  1. Elizabeth Fischer
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  2. Mikias Gebremeskel
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  3. Kochai Jan Jawed
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  4. Mahmut Ozturk
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  5. Kevin Cleary
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  6. Can Yerebakan
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Corresponding author

Correspondence to Elizabeth Fischer.

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Fischer, E., Gebremeskel, M., Jawed, K.J. et al. Development and assessment of novel assist device for cardiac cannulation. Int J CARS 19, 37–41 (2024). https://doi.org/10.1007/s11548-023-03013-x

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  • DOI: https://doi.org/10.1007/s11548-023-03013-x

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