Percutaneous lung biopsy: comparison between an augmented reality CT navigation system and standard CT-guided technique



Percutaneous lung biopsies (PLBs) performed for the evaluation of pulmonary masses require image guidance to avoid critical structures. A new CT navigation system (SIRIO, “Sistema robotizzato assistito per il puntamento intraoperatorio”) for PLBs was validated.


The local Institutional Review Board approved this retrospective study. Image-guided PLBs in 197 patients were performed with a CT navigation system (SIRIO). The procedures were reviewed based on the number of CT scans, patients’ radiation exposure and procedural time recorded. Comparison was performed with a group of 72 patients undergoing standard CT-guided PLBs. Sensitivity, specificity and overall diagnostic accuracy were assessed in both groups.


SIRIO-guided PLBs showed a significant reduction in procedure time, number of required CT scans and the radiation dose administered to patients (\(p<0.001\)). In terms of diagnostic accuracy, SIRIO proved to be more accurate for small-sized lesions (\(<\)20 mm) than standard CT-guidance.


SIRIO proved to be a reliable and effective tool when performing CT-guided PLBs and was especially useful for sampling small (\(<\)20 mm) lesions.

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Correspondence to R. L. Cazzato.

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Grasso, R.F., Faiella, E., Luppi, G. et al. Percutaneous lung biopsy: comparison between an augmented reality CT navigation system and standard CT-guided technique. Int J CARS 8, 837–848 (2013).

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  • Optical tracking
  • CT scan
  • Lung biopsy
  • Virtual navigation guidance