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Case-based lung image categorization and retrieval for interstitial lung diseases: clinical workflows

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International Journal of Computer Assisted Radiology and Surgery Aims and scope Submit manuscript

Abstract

Purpose

Clinical workflows and user interfaces of image-based computer-aided diagnosis (CAD) for interstitial lung diseases in high-resolution computed tomography are introduced and discussed.

Methods

Three use cases are implemented to assist students, radiologists, and physicians in the diagnosis workup of interstitial lung diseases.

Results

In a first step, the proposed system shows a three-dimensional map of categorized lung tissue patterns with quantification of the diseases based on texture analysis of the lung parenchyma. Then, based on the proportions of abnormal and normal lung tissue as well as clinical data of the patients, retrieval of similar cases is enabled using a multimodal distance aggregating content-based image retrieval (CBIR) and text-based information search. The global system leads to a hybrid detection-CBIR-based CAD, where detection-based and CBIR-based CAD show to be complementary both on the user’s side and on the algorithmic side.

Conclusions

The proposed approach is in accordance with the classical workflow of clinicians searching for similar cases in textbooks and personal collections. The developed system enables objective and customizable inter-case similarity assessment, and the performance measures obtained with a leave-one-patient-out cross-validation (LOPO CV) are representative of a clinical usage of the system.

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Authors and Affiliations

  1. MedGIFT Group, Business Information Systems, University of Applied Sciences Western Switzerland (HES-SO), Techno Ark 3, 3960, Sierre, Switzerland

    Adrien Depeursinge, Frédéric Gaillard & Henning Müller

  2. Service of Medical Informatics, University and University Hospitals of Geneva (HUG), Rue Gabrielle-Perret-Gentil 4, 1211, Geneva 14, Switzerland

    Alejandro Vargas & Antoine Geissbuhler

  3. Service of Emergency Radiology, HUG, Geneva, Switzerland

    Alexandra Platon & Pierre-Alexandre Poletti

Authors
  1. Adrien Depeursinge
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  2. Alejandro Vargas
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  3. Frédéric Gaillard
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  4. Alexandra Platon
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  5. Antoine Geissbuhler
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  6. Pierre-Alexandre Poletti
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  7. Henning Müller
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Correspondence to Adrien Depeursinge.

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Depeursinge, A., Vargas, A., Gaillard, F. et al. Case-based lung image categorization and retrieval for interstitial lung diseases: clinical workflows. Int J CARS 7, 97–110 (2012). https://doi.org/10.1007/s11548-011-0618-9

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  • DOI: https://doi.org/10.1007/s11548-011-0618-9

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