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Advanced CT techniques for assessing hepatocellular carcinoma

  • Abdominal Radiology
  • Published:
La radiologia medica Aims and scope Submit manuscript

Abstract

Hepatocellular carcinoma (HCC) is the sixth-most common cancer in the world, and hepatic dynamic CT studies are routinely performed for its evaluation. Ongoing studies are examining advanced imaging techniques that may yield better findings than are obtained with conventional hepatic dynamic CT scanning. Dual-energy CT-, perfusion CT-, and artificial intelligence-based methods can be used for the precise characterization of liver tumors, the quantification of treatment responses, and for predicting the overall survival rate of patients. In this review, the advantages and disadvantages of conventional hepatic dynamic CT imaging are reviewed and the general principles of dual-energy- and perfusion CT, and the clinical applications and limitations of these technologies are discussed with respect to HCC. Finally, we address the utility of artificial intelligence-based methods for diagnosing HCC.

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Funding

Kazuo Awai received a research grant from Canon Medical Systems Co. Ltd (A1700878).

Author information

Authors and Affiliations

  1. Diagnostic Radiology, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan

    Yuko Nakamura, Toru Higaki, Yukiko Honda, Fuminari Tatsugami, Chihiro Tani, Wataru Fukumoto, Keigo Narita, Shota Kondo, Motonori Akagi & Kazuo Awai

Authors
  1. Yuko Nakamura
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  2. Toru Higaki
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  3. Yukiko Honda
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  4. Fuminari Tatsugami
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  5. Chihiro Tani
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  6. Wataru Fukumoto
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  7. Keigo Narita
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  8. Shota Kondo
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  9. Motonori Akagi
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  10. Kazuo Awai
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Corresponding author

Correspondence to Yuko Nakamura.

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Nakamura, Y., Higaki, T., Honda, Y. et al. Advanced CT techniques for assessing hepatocellular carcinoma. Radiol med 126, 925–935 (2021). https://doi.org/10.1007/s11547-021-01366-4

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