La radiologia medica

, Volume 119, Issue 6, pp 400–407 | Cite as

Cardiac magnetic resonance before and after percutaneous pulmonary valve implantation

  • Francesco SecchiEmail author
  • Elda Chiara Resta
  • Luciane Piazza
  • Gianfranco Butera
  • Giovanni Di Leo
  • Mario Carminati
  • Francesco Sardanelli
Cardiac Radiology



To measure the magnetic resonance (MR) artefact produced by a percutaneous pulmonary valve stent and to evaluate the changes in volumetric and functional right ventricle (RV) parameters due to percutaneous pulmonary valve implantation (PPVI).

Materials and methods

A Melody valve was studied in vitro using clinical cardiac MR (CMR) sequences. In vivo, we analysed the CMR examinations obtained before and after PPVI of 27 consecutive patients. The echocardiography pressure gradient (PG) and catheter PG were measured. The Wilcoxon test was used for comparisons.


In vitro, the least difference between artefact extent and actual valve size (0.1 mm) was obtained with a steady-state free precession (SSFP) sequence. In vivo, RV end-diastolic volume (ml/m2), end-systolic volume (ml/m2) and ejection fraction (%) were 79 ± 42, 43 ± 41 and 49 ± 13 before PPVI and 64 ± 21 (p = 0.054), 30 ± 14 (p = 0.021), and 54 ± 12 (p = 0.018) 6 months after PPVI, respectively. The PG and regurgitation fraction (RF) were 36 ± 15 mmHg and 14 ± 18 % before PPVI and 13 ± 15 mmHg (p < 0.001) and 2 ± 5 % (p = 0.013) after PPVI, respectively. No significant differences were found comparing the PG measured with CMR, echocardiography and catheter.


We showed in vitro that the SSFP sequence produced the most accurate valve measurement. After PPVI, CMR showed a strong decrease of PG and RF with a significant improvement of RV function.


Congenital heart diseases Cardiac magnetic resonance (CMR) Percutaneous pulmonary valve implantation (PPVI) Right ventricle (RV) Pulmonary artery (PA) 


Conflict of interest

Francesco Secchi, Elda Chiara Resta, Luciane Piazza, Gianfranco Butera, Giovanni Di Leo, Mario Carminati, Francesco Sardanelli declare no conflict of interest.


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Copyright information

© Italian Society of Medical Radiology 2013

Authors and Affiliations

  • Francesco Secchi
    • 1
    Email author
  • Elda Chiara Resta
    • 2
  • Luciane Piazza
    • 3
  • Gianfranco Butera
    • 3
  • Giovanni Di Leo
    • 1
  • Mario Carminati
    • 3
  • Francesco Sardanelli
    • 1
    • 4
  1. 1.Unità di RadiologiaIRCCS Policlinico San DonatoSan Donato MilaneseItaly
  2. 2.Scuola di Specializzazione in RadiodiagnosticaUniversità degli Studi di MilanoMilanItaly
  3. 3.Unità di Cardiologia Pediatrica e Cardiopatie Congenite dell’AdultoIRCCS Policlinico San DonatoSan Donato MilaneseItaly
  4. 4.Dipartimento di Scienze Biomediche per la SaluteUniversità degli Studi di MilanoSan Donato MilaneseItaly

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