Skip to main content
Log in

Uncommon causes of tracheobronchial stenosis and wall thickening: MDCT imaging

Rare cause di stenosi e ispessimenti parietali della trachea e delle vie aeree principali: imaging TCMD

  • Chest Radiology Radiologia Toracica
  • Published:
La radiologia medica Aims and scope Submit manuscript


Some uncommon diseases may involve the central airways focally or diffusely. These include Wegener’s granulomatosis, relapsing polychondritis, tracheobronchopathia osteochondroplastica, amyloidosis, papillomatosis, rhinoscleroma, sarcoidosis and tuberculosis. Related computed tomography (CT) findings essentially include calcifications, luminal stenosis, wall thickening and nodules. The purpose of this paper is to help refine the differential diagnosis among these diseases through the use of multidetector CT (MDCT) imaging.


Alcune malattie di non frequente riscontro interessano localmente o diffusamente le vie aeree centrali. In questo gruppo di patologie sono incluse: la granulomatosi di Wegener, la policondrite ricorrente, la tracheobroncopatia osteocondroplastica, l’amiloidosi, la papillomatosi, il rinoscleroma, la sarcoidosi e la tubercolosi. Le alterazioni TC che si osservano in corso di queste patologie sono essenzialmente: calcificazioni, stenosi del lume, ispessimenti parietali e nodularità. Lo scopo del seguente pictorial essay è quello di tracciare la diagnosi differenziale fra queste malattie mediante imaging TC multidetettore (TCMD).

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others


  1. Cordier JF, Valere D, Guillevin L et al (1990) Pulmonary Wegener’s granulomatosis. A clinical and imaging study of 77 cases. Chest 97:906–912

    Article  PubMed  CAS  Google Scholar 

  2. McDonald TJ, Neel HB 3rd, DeRemee RA (1982) Wegener’s granulomatosis of the subglottis and the upper portion of the trachea. Ann Otol Rhinol Laryngol 91:588–592

    PubMed  CAS  Google Scholar 

  3. Langford CA, Sneller MC, Hallahan CW et al (1996) Clinical features and therapeutic management of subglottic stenosis in patients with Wegener’s granulomatosis. Arthritis Rheum 39:1754–1760

    Article  PubMed  CAS  Google Scholar 

  4. Stein MG, Gamsu G, Webb WR et al (1986) Computed tomography of diffuse tracheal stenosis in Wegener granulomatosis. J Comput Assist Tomogr 10:868–870

    Article  PubMed  CAS  Google Scholar 

  5. Kwong JS, Muller NL, Miller RR (1992) Diseases of the trachea and mainstem bronchi: correlation of CT with pathologic findings. Radiographics 12:645–657

    PubMed  CAS  Google Scholar 

  6. Screaton NJ, Sivasothy P, Flower CD et al (1998) Tracheal involvement in Wegener’s granulomatosis: evaluation using spiral CT. Clin Radiol 53:809–815

    Article  PubMed  CAS  Google Scholar 

  7. Eng J, Sabanathan S (1991) Airway complications in relapsing polychondritis. Ann Thorac Surg 51:686–692

    Article  PubMed  CAS  Google Scholar 

  8. McAdam LP, O’Hanlan MA, Bluestone R et al (1976) Relapsing polychondritis: prospective study of 23 patients and a review of the literature. Medicine 55:193–215

    Article  PubMed  CAS  Google Scholar 

  9. Behar JV, Choi YW, Hartman TA et al (2002) Relapsing polychondritis affecting the lower respiratory tract. Am J Roentgenol 178:173–177

    Google Scholar 

  10. Webb EM, Elicker BM, Webb WR (2000) Using CT to diagnose nonneoplastic tracheal abnormalities: appearance of the tracheal wall. AJR Am J Roentgenol 174:1315–1321

    PubMed  CAS  Google Scholar 

  11. Prakash UB, McCullough AE, Edell ES et al (1989) Tracheopathia osteoplastica: familial occurrence. Mayo Clinic Proc 64:1091–1096

    CAS  Google Scholar 

  12. Wong JS, Ng CS, Yim AP (2005) Hemoptysis with multiple tracheal nodules. Chest 128:3671–3673

    Article  PubMed  Google Scholar 

  13. Mariotta S, Pallone G, Pedicelli G et al (1997) Spiral CT and endoscopic findings in a case of tracheobronchopathia osteochondroplastica. J Comput Assist Tomogr 21:418–420

    Article  PubMed  CAS  Google Scholar 

  14. Manning JE, Golding JG, Shpiner RB et al (1998) Case report: tracheobronchopathia osteochondroplastica. Clin Radiol 53:302–309

    Article  PubMed  CAS  Google Scholar 

  15. Urban BA, Fishman EK, Goldman SM et al (1993) CT evaluation of amyloidosis: spectrum of disease. Radiographics 13:1295–1308

    PubMed  CAS  Google Scholar 

  16. Kim HY, Im JG, Song KS et al (1999) Localized amyloidosis of the respiratory system: CT features. J Comput Assist Tomogr 23:627–631

    Article  PubMed  CAS  Google Scholar 

  17. Pickford HA, Swensen SJ, Utz JP (1997) Thoracic cross-sectional imaging of amyloidosis. AJR Am J Roentgenol 168:351–355

    PubMed  CAS  Google Scholar 

  18. Farrell M, McAdams HP, Erasmus JJ (1999) A 27-year-old woman with cough, dyspnea, and wheezing. Chest 116:557–559

    Article  PubMed  CAS  Google Scholar 

  19. Wilson SR, Sanders DE, Delarue NC (1976) Intrathoracic manifestations of amyloid disease. Radiology 120:283–289

    PubMed  CAS  Google Scholar 

  20. Chen KT (1989) Amyloidosis presenting in the respiratory tract. Phatol Annu 24:253–273

    Google Scholar 

  21. Kirchner J, Jacobi V, Kardos P et al (1998) CT findings in extensive tracheobronchial amyloidosis. Eur Radiol 8:352–354

    Article  PubMed  CAS  Google Scholar 

  22. Chaoui AS, Barish MA, Fenlon HM (1999) Thoracic case of the day. Primary diffuse tracheobronchial amyloidosis. AJR Am J Roentgenol 173:823–828

    PubMed  CAS  Google Scholar 

  23. Lam CW, Talbot AR, Yeh KT et al (2004) Human papillomavirus and squamous cell carcinoma in a solitary tracheal papilloma. Ann Thorac Surg 77:2201–2202

    Article  PubMed  Google Scholar 

  24. Hartley C, Hamilton J, Birzgalis AR et al (1994) Recurrent respiratory papillomatosis-the Manchester experience, 1974–1992. J Laryngol Otol 108:226–229

    PubMed  CAS  Google Scholar 

  25. Gruden JF, Webb WR, Sides DM (1994) Adult-onset disseminated tracheobronchial papillomatosis: CT features. J Comput Assist Tomogr 18:640–642

    Article  PubMed  CAS  Google Scholar 

  26. Brandstetter RD, Messina MS, Sprince NL et al (1981) Tracheal stenosis due to sarcoidosis. Chest 80:656

    Article  PubMed  CAS  Google Scholar 

  27. Jokinen K, Palva T, Nuutinen J (1977) Bronchial findings in pulmonary tuberculosis. Clin Otolaryngol Allied Sci 2:139–148

    Article  PubMed  CAS  Google Scholar 

  28. Choe KO, Jeong HJ, Sohn HY (1990) Tuberculous bronchial stenosis: CT Findings in 28 cases. AJR Am J Roentgenol 155:971–976

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to A. Ingegnoli.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ingegnoli, A., Corsi, A., Verardo, E. et al. Uncommon causes of tracheobronchial stenosis and wall thickening: MDCT imaging. Radiol med 112, 1132–1141 (2007).

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI:

Key words

Parole chiave