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La radiologia medica

, Volume 112, Issue 2, pp 287–303 | Cite as

Real-time reading in mammography breast screening

  • R. MariottoEmail author
  • B. Brancato
  • F. Bonetti
  • E. Manfrin
  • M. Strabbioli
  • A. Mercanti
  • F. Falsirollo
  • P. Bricolo
  • G. F. Pistolesi
BREAST RADIOLOGY

Abstract

Purpose.

This study was undertaken to assess the role of real-time reading in the mammography screening programme carried out at the Hospital of Marzana, Verona, Italy.

Materials and methods.

During the 5-year period 1999–2004, 54,472 women attended the screening programme (32,291 first calls: unadjusted uptake 41.4%, adjusted uptake 50.3%; 21,551 2- year routine recalls: unadjusted uptake 86.4%, adjusted uptake 89.9%). Further diagnostic investigations [(FDI), imaging and cytohistological] were performed immediately after real-time reading of the screening mammograms (FDI rate among first calls 10.9%; FDI rate among 2-year recalls 5.4%). Overall, cytohistological FDI were requested in 27% of imaging FDI, with a clear prevalence of cytological [fine-needle aspiration cytology (FNAC) 87%] over histological procedures [core needle biopsy (CNB) 11%; vacuum aspiration biopsy (VAB) 2%].

Results.

Imaging FDI proved to be conclusive in 73%. Cytohistological FDI led to the use of surgical biopsy (SB) in 39.5% (ratio between benign and malignant SB: 0.19/first calls, 0.14/2-year recalls). There were a total of 427 screen-detected breast cancers (BC), with a very good breast cancer detection rate (BCDR/first calls 9.7‰; BCDR/2-year recalls 5.1‰). In the 427 screen-detected BC, the incidence of pTis, pT1a,b cancers was 59.6% (diagnostic anticipation); the incidence of pN0 cancers was 61.2%; the incidence of conservative surgical procedures was 78.6%. In interval cancers, the false negative rate was 8.3% only, whereas the proportional incidence was very low indeed (14% first year; 38% second year).

Conclusions.

The high sensitivity exhibited by the Marzana mammography screening programme suggests that the value of real-time reading should be validated by other programmes adopting a similar approach.

Key words

Mammography breast screening Real-time reading 

Screening mammografico con lettura in "tempo reale"

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Copyright information

© Springer-Verlag Italia 2007

Authors and Affiliations

  • R. Mariotto
    • 1
    • 6
    Email author
  • B. Brancato
    • 2
  • F. Bonetti
    • 3
  • E. Manfrin
    • 3
  • M. Strabbioli
    • 1
  • A. Mercanti
    • 4
  • F. Falsirollo
    • 1
  • P. Bricolo
    • 1
  • G. F. Pistolesi
    • 5
  1. 1.Centro di Prevenzione SenologicaOspedale di MarzanaVeronaItaly
  2. 2.Unità Operativa di Senologia del C.S.P.O.FirenzeItaly
  3. 3.Istituto di Anatomia PatologicaUniversità degli Studi di VeronaVeronaItaly
  4. 4.Istituto di Oncologia Medica, Policlinico "G.B. Rossi"Università degli Studi di VeronaVeronaItaly
  5. 5.Professore Emerito di Radiologia della UniversitàVerona - Casa di Cura "Villa Lieta"VeronaItaly
  6. 6.Servizio di Radiologia, Ospedale "C. Poma"MantovaItaly

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