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Mimicking catalase and catecholase enzymes by copper(II)-containing complexes

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Central European Journal of Chemistry

Abstract

An imidazolate-bridged copper(II)-zinc(II) complex (Cu(II)-diethylenetriamino-μ-imidazolato-Zn(II)-tris(2-aminoethyl)amine perchlorate (denoted as “Cu,Zn complex”) and a simple copper(II) complex (Cu(II)-tris(2-aminoethyl) amine chloride (“Cu-tren”) were prepared and immobilised on silica gel (by hydrogen or covalent bonds) and montmorillonite (by ion exchange). The immobilised substances were characterised by FT-IR spectroscopy and their thermal characteristics were also studied. The obtained materials were tested in two probe reactions: catalytic oxidation of 3,5-di-tert-butyl catechol (DTBC) (catecholase activity) and the decomposition of hydrogen peroxide (catalase activity). It was found that the catecholase activity of the Cu,Zn complex increased considerably upon immobilization on silica gel via hydrogen bonds and intercalation by ion exchange among the layers of montmorillonite. The imidazolate-bridged copper(II)-zinc(II) complex and its immobilised versions were inactive in hydrogen peroxide decomposition. The Cu(II)-tris(2-aminoethyl)amine chloride complex displayed good catalase activity; however, immobilisation could not improve it.

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Authors and Affiliations

  1. Department of Inorganic and Analytical Chemistry, University of Szeged, Dóm tér 7, H-6720, Szeged, Hungary

    István Szilágyi, László. Horváth, Imre Labádi & Tamás Kiss

  2. Department of Applied and Environmental Chemistry, University of Szeged, Rerrich B. tér 1, H-6720, Szeged, Hungary

    Klara Hernadi

  3. Department of Organic Chemistry, University of Szeged, Dóm tér 8, H-6720, Szeged, Hungary

    István Pálinkó

  4. Bioinorganic Chemistry Research Group of the Hungarian Academy of Sciences, University of Szeged, Dóm tér 7, H-6720, Szeged, Hungary

    Tamás Kiss

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  1. István Szilágyi
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Szilágyi, I., Horváth, L., Labádi, I. et al. Mimicking catalase and catecholase enzymes by copper(II)-containing complexes. cent.eur.j.chem. 4, 118–134 (2006). https://doi.org/10.1007/s11532-005-0009-6

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  • DOI: https://doi.org/10.1007/s11532-005-0009-6

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