High-Risk Geographic Mobility Patterns among Young Urban and Suburban Persons who Inject Drugs and their Injection Network Members
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Young people in the USA who inject drugs, particularly those at a risk of residence instability, experience the highest incidence of hepatitis C (HCV) infections. This study examined associations between geographic mobility patterns and sociodemographic, behavioral, and social network characteristics of 164 young (ages 18–30) persons who inject drugs (PWID). We identified a potential bridge sub-population who reported residence in both urban and suburban areas in the past year (crossover transients) and higher-risk behaviors (receptive syringe sharing, multiple sex partners) compared to their residentially localized counterparts. Because they link suburban and urban networks, crossover transients may facilitate transmission of HIV and HCV between higher and lower prevalence areas. Interventions should address risk associated with residential instability, particularly among PWID who travel between urban and suburban areas.
KeywordsPersons who inject drugs Injection drug use Hepatitis C Transience Mobility Suburban
Compliance with Ethical Standards
The study was approved by the Institutional Review Board of the University of Illinois at Chicago.
This study was funded by a pilot grant award from the Chicago Developmental Center for AIDS Research (Grant#5P30AI082151–04). Other funding to support work on this manuscript include an NIH grant (R01-AI078881) and internal funding from Loyola University Chicago. The funding sources were not directly involved in the collection, analysis, or interpretation of the data; in the writing of this report; or in the decision to submit the paper for publication.
- 4.Zibbell JE, Iqbal K, Patel RC, et al. Increases in hepatitis C virus infection related to injection drug use among persons aged </=30 years—Kentucky, Tennessee, Virginia, and West Virginia, 2006-2012. Morb Mortal Wkly Rep. 2015;64(17):453–8.Google Scholar
- 5.Centers for Disease Control and Prevention: Viral hepatitis surveillance. http://www.cdc.gov/hepatitis/statistics/2013surveillance/pdfs/2013hepsurveillancerpt.pdf (2013). Accessed July 20, 2016.
- 6.Centers for Disease Control and Prevention. Hepatitis C virus infection among adolescents and young adults: Massachusetts, 2002-2009. Morb Mortal Wkly Rep. 2011;60(17):537–41.Google Scholar
- 7.Leuchner L, Lindstrom H, Burstein GR, et al. Use of enhanced surveillance for hepatitis C virus infection to detect a cluster among young injection-drug users—New York, November 2004-April 2007 (reprinted from Morb Mortal Wkly Rep., vol 57, pg 517-521, 2008). J Am Med Assoc. 2008;300(1):34–6.CrossRefGoogle Scholar
- 9.Centers for Disease C, Prevention. Notes from the field: hepatitis C virus infections among young adults--rural Wisconsin, 2010. Morb Mortal Wkly Rep. 2012;61(19):358.Google Scholar
- 10.Centers for Disease Control and Prevention. Use of enhanced surveillance for hepatitis C virus infection to detect a cluster among young injection-drug users, New York, November 2004-April 2007. Morb Mortal Wkly Rep. 2008;57(19):517–21.Google Scholar
- 19.Centers for Disease Control and Prevention. Estimated HIV incidence in the United States, 2007–2010. HIV Surveillance Supplemental Report 2012;17(No. 4). http://www.cdc.gov/hiv/topics/surveillance/resources/reports/%23supplemental. Published December 2012. Accessed August 1, 2017.
- 21.Spiller MW, Broz D, Wejnert C, Nerlander L, Paz-Bailey G. HIV infection and HIV-associated behaviors among persons who inject drugs—20 cities, United States, 2012. Morb Mortal Wkly Rep. 2015;64(10):270–5.Google Scholar
- 23.Khan MR, Berger A, Hemberg J, O’Neill A, Dyer TP, Smyrk K. Non-injection and injection drug use and STI/HIV risk in the United States: the degree to which sexual risk behaviors versus sex with an STI-infected partner account for infection transmission among drug users. AIDS Behav. 2013;17(3):1185–94.CrossRefPubMedPubMedCentralGoogle Scholar
- 36.Project Know. Arrests across America: the current drug landscape. http://www.projectknow.com/discover/drug-arrest-across-america/#chi. Accessed July 30, 2016.
- 38.Chicago Department of Public Health. HIV/STI Surveillance Report 2016. Chicago, IL: City of Chicago, December 2016. https://www.cityofchicago.org/content/dam/city/depts/cdph/HIV_STI/World_AIDS_Day_Report_012717.pdf. Accessed August 1, 2017.
- 39.Cook County Department of Public Health. HIV/AIDS Surveillance Report, 2006–2008. Oak Park, IL; 2010. www.cookcountypublichealth.org/files/pdf/HIVAIDS2006to2008Final.pdf. Accessed August 1, 2017.
- 48.U.S. Department of Health and Human Services: Action plan for the prevention, care, & treatment of viral hepatitis. http://www.cdc.gov/hepatitis/HHS-ActionPlan.htm (2014). Accessed December 15, 2016.
- 51.Sadler MD, Lee SS. Revolution in hepatitis C antiviral therapy. Br Med Bull.. 2015;113(1):31–44.Google Scholar
- 52.Dahari H, Cotler SJ, Feld JJ. Cure prevents more than transmission of HCV. Hepatology. 2016;64(3):1003–4.Google Scholar
- 59.Martin NK, Vickerman P, Grebely J, et al. Hepatitis C virus treatment for prevention among people who inject drugs: Modeling treatment scale-up in the age of direct-acting antivirals. Hepatology. 2013;58(5):1598–609.Google Scholar