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Proof of concept percutaneous treatment system to enable fast and finely controlled ablation of biological tissue

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Abstract

A prototype system has been developed for producing controllable ablation of spherical lesions with a diameter of up to 2 cm. The system is based on a solid-state energy source operating in the super high frequency (SHF is sdefined as being a frequency of between 3 and 30 GHz) region of the electromagnetic spectrum. Results obtained from preliminary tissue testing, performed on morbid tissue samples prepared in a laboratory environment, show repeatability in terms of shape and size of ablation, and demonstrate the ability to produce controlled ablation in morbid liver and kidney models.

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Acknowledgments

C. H. would like to thank all the people who supported this work. Special thanks to Steve Morris, Izzat Darwazeh, John Bishop, Warren Jones, Robin Sloan, Simon Burdett, Andy Goodman, Richard Owen, Sabih Chaudhry and Graham Evans. The financial and clinical support of MDi Ltd is also gratefully acknowledged.

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Authors and Affiliations

  1. MicroOncology Ltd, First Floor, Unit 6, Brassmill Enterprise Centre, Brassmill Lane, B&NES, Bath, BA1 3JN, UK

    C. P. Hancock, S. Chaudhry & A. M. Goodman

  2. Medical Devices Innovations Ltd (MDi), Daresbury Innovation Centre, Daresbury Science and Innovation Campus, Halton, Cheshire, WA4 4FS, UK

    P. Wall

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  1. C. P. Hancock
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  2. S. Chaudhry
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  3. P. Wall
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  4. A. M. Goodman
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Correspondence to C. P. Hancock.

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Hancock, C.P., Chaudhry, S., Wall, P. et al. Proof of concept percutaneous treatment system to enable fast and finely controlled ablation of biological tissue. Med Bio Eng Comput 45, 531–540 (2007). https://doi.org/10.1007/s11517-007-0184-z

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  • DOI: https://doi.org/10.1007/s11517-007-0184-z

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