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Dielectric relaxation of a protein–water system in atherosclerotic artery wall

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Abstract

Measurements of the dielectric properties of healthy and atherosclerotic human artery tissues were made in the frequency range of 100 Hz–100 kHz and temperatures from 22 to 260°C. The temperature dependencies of the dielectric parameters for healthy tissues reveal distinctively the temperature ranges corresponding to the release of water up to 200°C and the decomposition processes of elastin and collagen, above this temperature. The influence of atherosclerosis on the dielectric properties of artery tissues is significant in the whole temperature range. The relative permittivity for atherosclerotic tissues at the same temperature is much lower than for the healthy tissues. This suggests, that the polarization in atherosclerotic tissues due to protons hopping between a smaller number of sites than in healthy tissues, as a results of the thermal degradation of collagen–water. The data obtained above 200°C indicate that the atherosclerosis induces the higher physico-chemical changes in the collagen when compared to elastin.

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Authors and Affiliations

  1. Department of General and Vascular Surgery, Poznań University of Medical Sciences, Długa ½, 61-848, Poznan, Poland

    J. Brzeziński & G. Oszkinis

  2. Department of Biophysics, Poznań University of Medical Sciences, Fredry 10, 61-701, Poznan, Poland

    E. Marzec

Authors
  1. J. Brzeziński
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  2. G. Oszkinis
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  3. E. Marzec
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Correspondence to E. Marzec.

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Brzeziński, J., Oszkinis, G. & Marzec, E. Dielectric relaxation of a protein–water system in atherosclerotic artery wall. Med Bio Eng Comput 45, 525–529 (2007). https://doi.org/10.1007/s11517-007-0181-2

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  • DOI: https://doi.org/10.1007/s11517-007-0181-2

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