A modified resonant recognition model to predict protein-protein interaction
- 65 Downloads
Proteins are fundamental components of all living cells and the protein-protein interaction plays an important role in vital movement. This paper briefly introduced the original Resonant Recognition Model (RRM), and then modified it by using the wavelet transform to acquire the Modified Resonant Recognition Model (MRRM). The key characteristic of the new model is that it can predict directly the protein-protein interaction from the primary sequence, and the MRRM is more suitable than the RRM for this prediction. The results of numerical experiments show that the MRRM is effective for predicting the protein-protein interaction.
Keywordsprotein-protein interaction resonant recognition model modified resonant recognition model discrete wavelet transform characteristics frequency
Unable to display preview. Download preview PDF.
- Bartel P L, Fields S (1997). The yeast two-hybrid system. In: Advances in Molecular Biology. New York: Oxford University PressGoogle Scholar
- Cosic I (1999). The resonant recognition model of macromolecular bioactivity. BioMethod, 8Google Scholar
- Daubechies I (1992). Ten Lectures on Wavelets. Society for Industrial and Applied Mathematics. Philadelphia.Google Scholar
- Ladik J (1974). All valence electron band structures of simple periodic protein models. Int J Quantum Chemistry Quantum Biol Symp, 1: 65–69Google Scholar
- Pirogova E, Cosic I (1999). Proc.of IEEE EMBS VIC Australia, 203–206Google Scholar
- Uetz P, Giot L, Cagney, G, Mansfield T A, Judson R S, Knight J R, Lockshon D, Narayan V, Srinivasan M, Pochart P, Qureshi-Emili A, Li Y, Godwin, B, Conover D, Kalbfleisch T, Vijayadamodar G, Yang M, Johnston M, Fields S, Rothberg J M (2000). A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature, 403(6770): 623–627PubMedCrossRefGoogle Scholar