Abstract
Nano-size catechin/β-cyclodextrin inclusion complex (CA/β-CD IC) with 1:1 molar ratio was obtained by cooling precipitation at 4 °C. Physicochemical properties of the CA/β-CD IC nanoparticles were characterized. Results of dynamic light scattering and SEM observation showed that CA/β-CD IC molecules underwent a process of assembling and shaping nano-size particles. In the range of 10–14 mM, the higher the concentration of β-CD aqueous solution, the faster the CA/β-CD IC nanoparticles form and the larger the size of the nanoparticles (195.2–438.6 nm). The total recovery, inclusion ratio and loading capacity of the CA/β-CD IC nanoparticles were determined. Results of FT-IR and DSC indicated that stability of CA was enhanced after it was embedded into β-CD cavity. XRD results showed that the strongest three diffraction peaks (located at 2θ = 10.6°, 12.4° and 19.6°) of the CA/β-CD IC nanoparticles was different from that (located at 2θ = 6.6°, 11.7° and 17.7°) of micro-size CA/β-CD IC and the nanoparticles obtained from higher concentration solution possessed higher crystallinity.
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This work was supported by the Natural Science Foundation of Jilin Province (project number 20200201105JC) and Jilin Province Development and Reform Commission (project number 2019C059-8).
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Jiang, L., Wang, P., Kou, L. et al. Preparation and Physicochemical Properties of Catechin/β-cyclodextrin Inclusion Complex Nanoparticles. Food Biophysics 16, 317–324 (2021). https://doi.org/10.1007/s11483-021-09672-0
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DOI: https://doi.org/10.1007/s11483-021-09672-0