Skip to main content

Application of LIBS in Detection of Antihyperglycemic Trace Elements in Momordica charantia

Food Biophysics volume 4, pages 167–171 (2009)Cite this article

Abstract

The present study exploits the information based on concentration of trace elements and minerals in understanding the role/mechanism of action of freeze-dried fruit powder suspended in distilled water of Momordica charantia (family: Cucurbitaceae) in diabetes treatment. Laser-induced break down spectroscopy (LIBS) spectra of plant product was recorded under optimized experimental conditions and analyzed. Several atomic lines such as Na, K, Mg, Ca, Fe, Al, etc. have been observed in the LIBS spectra of the above plant product. The concentrations of these minerals are determined by using calibration-free LIBS method. Correlation between the concentration of these elements/minerals and their defined role in diabetes management was studied in normal as well as diabetic animal models.

This is a preview of subscription content, access via your institution.

Access options

Buy single article

Instant access to the full article PDF.

39,95 €

Price includes VAT (Finland)

Fig. 1

References

  1. P.K. Rai, S.K. Singh, A.N. Kessari, G. Watal, Indian J. Med. Res. 126, 224–227 (2007)

    CAS  Google Scholar 

  2. P.K. Rai, N.K. Rai, A.K. Rai, G. Watal, Inst. Sc. Tech. 35, 507–522 (2007). doi:10.1080/10739140701540230

    Article  CAS  Google Scholar 

  3. J.K. Grover, S.P. Yadav, J. Ethnopharmacol. 93, 123–132 (2004). doi:10.1016/j.jep.2004.03.035

    Article  CAS  Google Scholar 

  4. E. Basch, S. Gabardi, C. Ulbricht, Am. J. Health Syst. Pharm. 60, 356–359 (2003)

    Google Scholar 

  5. D.A. Cremers, L.J. Radziemski, in Laser Induced Breakdown Spectroscopy: Fundamentals and Applications, ed. by A.W. Miziolek, V. Palleschi, I. Schechter (Cambridge University Press, New York, 2006), pp. 1–40. ch. 1

    Chapter  Google Scholar 

  6. B. Bousquet, J.B. Sirven, L. Canioni, Spectrochim. Acta, Part B: Atom Spectrosc. 62, 1582–1589 (2007). doi:10.1016/j.sab.2007.10.018

    Article  Google Scholar 

  7. S. Pandhija, A.K. Rai, Pramana 70, 553–563 (2008). doi:10.1007/s12043-008-0070-8

    Article  CAS  Google Scholar 

  8. O. Smaek, D.C.S. Beddows, J. Kaiser, S.V. Kukhlevsky, M. Liska, H.H. Telle, J. Young, Opt. Eng. 39, 2248–2262 (2000). doi:10.1117/1.1304855

    Article  Google Scholar 

  9. S.N. Thakur, J.P. Singh, in Laser Induced Breakdown Spectroscopy, ed. by J.P. Singh, S.N. Thakur (Elsevier Science, Amsterdam, 2007), pp. 1–19. ch. 1

    Google Scholar 

  10. A.K. Rai, V.N. Rai, F.Y. Yueh, J.P. Singh, Trends Appl. Spectrosc. 4, 165–214 (2002)

    CAS  Google Scholar 

  11. V.K. Singh, V. Rai, A.K. Rai, Lasers Med. Sci. 24, 27–33 (2009). doi:10.1007/s10103-007-0516-0

    Article  Google Scholar 

  12. A. Ciucci, M. Corsi, V. Palleschi, S. Rastelli, A. Salvetti, E. Tognoni, Appl. Spectrosc. 53, 960–964 (1999). doi:10.1366/0003702991947612

    Article  CAS  Google Scholar 

  13. D. Brahm, P. Trinder, Analyst (Lond) 97, 142–145 (1972). doi:10.1039/an9729700142

    Article  Google Scholar 

  14. S. Pandhija, A. K. Rai, Appl. Phys., B Lasers Opt., 94, 545–552 (2009). doi:10.1007/s00340-008-3343-5

  15. M. Hoenig, A. de Kersabiec, Spectrochim. Acta, Part B: Atom Spectrosc. 51, 1297–1307 (1996)

    Article  Google Scholar 

  16. M. Hoenig, H. Baeten, S. Vanhentenrijk, E. Vasileva, P. Quevauviller, Anal. Chim. Acta. 358, 85–94 (1998). doi:10.1016/S0003-2670(97)00594-1

    Article  CAS  Google Scholar 

  17. E.J. Underwood, W. Mertz, Trace elements in human and animal nutrition, vol 1 (Academic, New York, 1986), pp. 11–17

    Google Scholar 

  18. Elson M, Haas MD, Role of potassium in maintaining health, (2007). http://www.hkpp.org/general/potassium_health.html

  19. G.L. Yeh, D.M. Eisenberg, T.J. Kaptchuk, R.S. Phillips, Diabetes Care 26, 1277–1294 (2003). doi:10.2337/diacare.26.4.1277

    Article  CAS  Google Scholar 

  20. R.L. Ridaura, W.C. Willett, E.B. Rimm, S. Liu, M.J. Stampeer, J.E. Manson, F.B. Hu, Diabetes Care 27, 134–140 (2004). doi:10.2337/diacare.27.1.134

    Article  Google Scholar 

  21. A. Kar, B.K. Choudhary, N.G. Bandyopadhyaya, J. Ethnopharmacol. 64, 179–184 (1999). doi:10.1016/S0378-8741(98)00118-4

    Article  CAS  Google Scholar 

Download references

Acknowledgment

Financial assistance from SASE, DRDO is highly acknowledged. Authors are also thankful to Mr. D. N. Junjun wala (Jhoola Herba cares) for freeze-drying M. charantia fruits.

Author information

Authors and Affiliations

  1. Laser spectroscopy research laboratory, Department of Physics, University of Allahabad, Allahabad, 211002, India

    Nilesh K. Rai, Shiwani Pandhija & A. K. Rai

  2. Alternative Therapeutics Unit, Drug Discovery & Development Division, Medicinal Research Lab, Department of Chemistry, University of Allahabad, Allahabad, 211002, India

    Prashant Kumar Rai & Geeta Watal

  3. Laboratory of Biophysics, Department of Agrotechnology and Food Sciences, Wageningen University, Dreijenlaan 3-Transitorium, 6703 HA, Wageningen, The Netherlands

    Dane Bicanic

Authors
  1. Nilesh K. Rai
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Prashant Kumar Rai
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Shiwani Pandhija
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Geeta Watal
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. A. K. Rai
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Dane Bicanic
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Geeta Watal or A. K. Rai.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Rai, N.K., Rai, P.K., Pandhija, S. et al. Application of LIBS in Detection of Antihyperglycemic Trace Elements in Momordica charantia . Food Biophysics 4, 167–171 (2009). https://doi.org/10.1007/s11483-009-9114-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11483-009-9114-y

Keywords

  • Momordica charantia
  • Diabetes
  • LIBS
  • Indian herbs
  • Cucurbitaceae