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Synthesis and Optical Properties of Highly Stabilized Peptide-Coated Gold Nanoparticles

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Abstract

The interaction between peptide and gold nanoparticle surfaces has been increasingly of interest for bionanotechnology applications. To fully understand how to control such interactions, we have studied the optical properties of peptide-modified gold nanoparticles. However, the impacts of peptide binding motif upon the surface characteristics and physicochemical properties of nanoparticles remain poorly understood. Here, we have prepared sodium citrate-stabilized gold nanoparticles and coated with peptide IVD (ID3). These nanomaterials were characterized by UV-visible, transmission electron microscopy (TEM), and z-potential measurement. The results indicate that gold-peptide interface is generated using ID3 peptide and suggested that the reactivity of peptide is governed by the conformation of the bound peptide on the nanoparticle surface. The peptide-nanoparticle interactions could potentially be used to make specific functionality into the peptide capped nanomaterials.

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Acknowledgments

The authors would like to thank WPI, USA, and IISc, Bangalore, India, for the financial support.

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Authors and Affiliations

  1. Department of Materials Science and Engineering, Carnegie Mellon University, Pittsburgh, PA, 15213, USA

    P. Kalakonda

  2. Department of Physics, Indian Institute of Science, Bangalore, KA, India

    P. Kalakonda

  3. Department of Chemistry, Chongqing University, Chongqing, 401331, China

    B. Sreenivas

Authors
  1. P. Kalakonda
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  2. B. Sreenivas
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Corresponding author

Correspondence to P. Kalakonda.

Electronic Supplementary Material

Fig. S1

FTIR spetra of gold nanoparticles (DOCX 53 kb)

Fig. S2

The photo luminance (PL) spectra of GNPs as the function of wavelength at different excitation wavelengths (b) The PL peak intensity of GNP as the function of GNP concentrations at different excitation wavelengths. (DOCX 268 kb)

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Kalakonda, P., Sreenivas, B. Synthesis and Optical Properties of Highly Stabilized Peptide-Coated Gold Nanoparticles. Plasmonics 12, 1221–1225 (2017). https://doi.org/10.1007/s11468-016-0379-y

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  • DOI: https://doi.org/10.1007/s11468-016-0379-y

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