Abstract
To study the bioactive constituents from Andrographis paniculata, two compounds were isolated and purified by column chromatography on AB-8 macro-porous adsorption resin and polyamide. Their structures were determined by various spectroscopic methods, including UV, FABMS, 1H-NMR, 13C-NMR, DQFCOSY, TOCSY, HMQC, HMBC, and NOESY. The 1H-NMR and 13C-NMR signals of the two compounds were assigned. The structures of the two compounds were elucidated as 5,4′-dihydroxy-7-methoxyflavone-6-yl-β-D-glucopyranoside and 5,4′-dihydroxy-7-methoxyflavone-8-yl-β-Dglucopyranoside, respectively.
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Wang G C, Hu Y M, Zhang X Q, Ye W C. Chemical constituents from leaves of andrographis paniculata. J China Pharm Univ, 2005, 36(5): 405–407 (in Chinese)
Gao F J, Zhang W G, Zhou S N, Yan T X, Lu, X Y. The progresses of studies on cardiovascular pharmacology of Andrographis paniculata. Chin Tradit Herb drugs, 2000, 31(10), append 6–8 (in Chinese)
Wang H W, Li Sh Sh, Zhao H Y, Wang G P. Effects of API0134 on thrombus formation and platelet signaling in rabbits with high cholesterolemia. China J Arteriosolerosis, 2002, 10(4): 285–287 (in Chinese)
Krishnaswamy N R, Nageawara Rao G, Omana P. Lipids and flavonoids from Sesamum Laciniatum Klein. Indian Jounal of Chemistry, 1995, 34B: 750–752
Harborne J B, Williams Ch A. 6-Hydroxyflavones and other flavonoids of Crocus. Z. Naturforsch, 1984, 39c: 18–23
Saxena S, Jain D C. Phytochemicals from Andrographis paniculata. Indian Jounal of Chemistry, 2003, 42B: 3159–3163
Zhang Y E, Ruan J L, Ding W P. The application of 13C-NMR in the study on the structure of C21 steroidal saponins. World Phytomed, 1992, 7(2): 51–56 (in Chinese)
Peng J Y, Fan G R, Wu Y T. Studies on chemical constituents of Patrinia Villosa. China J Chin Mat. Med 2006, 31(2): 128–130(in Chinese)
Wang H Y, Xiao L H, Liu L, Xu S X. Studies on chemical constituents of the roots of Scutellaria viscidulabge. J Shenyang Pharm Univ, 2003, 20(5): 339–341; 348 (in Chinese)
Wang X, Qin M J, Wu G, Shu P. Chemical constituents of the leaves of Iris songaric. J China Pharm Univ, 2006, 37(3): 222–225 (in Chinese)
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Translated from Acta Chimica Sinica, 2007, 65(14): 1399–1402 [译自: 化学学报]
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Ren, X., Du, G., Zhou, B. et al. Study on spectroscopy of two flavonyl glycosides from Andrographis paniculata . Front. Chem. China 3, 178–181 (2008). https://doi.org/10.1007/s11458-008-0034-z
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DOI: https://doi.org/10.1007/s11458-008-0034-z