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Effect of Jiaji electroacupuncture in transected rat spinal cord

  • Article
  • Preclinical Medicine
  • Open Access
  • Published: 08 December 2011
  • volume 57, pages 762–768 (2012)
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Chinese Science Bulletin
Effect of Jiaji electroacupuncture in transected rat spinal cord
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  • XiuYing Teng1,
  • DeSheng Wang1,
  • XiaoMei Zhang1,
  • ZengJiao Lai1,
  • HaiXia Jiang1,
  • JianLi Wu1,
  • Huan Qi1,
  • Qian Yu1,
  • Shun Yao1,
  • WenBo Song1,
  • JingJie Yang1 &
  • …
  • AiMu Li1 
  • 821 Accesses

  • 1 Citation

  • Explore all metrics

  • Cite this article

Abstract

We evaluated the effect of Jiaji electroacupuncture on cell proliferation and the expression of markers of endogenous neural stem cell activation after complete spinal cord transection. Female Wistar rats were assigned to 4 groups (n = 24 each): a sham-operated group, a control group, a Jiaji electroacupuncture group, and a Jiaji electroacupuncture preconditioning group. Motor function was significantly improved in the acupuncture groups compared to the control group at 7 and 14 d. Numbers of bromodeoxyuridine (BrdU)-, nestin-, and glial fibrillary acidic protein (GFAP)-positive cells were significantly greater in the acupuncture groups than in the controls at each time point. Expression of nestin and GFAP mRNA was significantly higher in the acupuncture groups than in the controls at each time point. Thus, Jiaji electroacupuncture and preconditioning may promote the proliferation of endogenous neural stem cells after spinal cord transection.

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Authors and Affiliations

  1. The First Affiliated Hospital of Harbin Medical University, Harbin, 150040, China

    XiuYing Teng, DeSheng Wang, XiaoMei Zhang, ZengJiao Lai, HaiXia Jiang, JianLi Wu, Huan Qi, Qian Yu, Shun Yao, WenBo Song, JingJie Yang & AiMu Li

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  1. XiuYing Teng
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  2. DeSheng Wang
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Correspondence to DeSheng Wang.

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Cite this article

Teng, X., Wang, D., Zhang, X. et al. Effect of Jiaji electroacupuncture in transected rat spinal cord. Chin. Sci. Bull. 57, 762–768 (2012). https://doi.org/10.1007/s11434-011-4839-7

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  • Received: 30 April 2011

  • Accepted: 22 June 2011

  • Published: 08 December 2011

  • Issue Date: March 2012

  • DOI: https://doi.org/10.1007/s11434-011-4839-7

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Keywords

  • Jiaji electroacupuncture
  • spinal transection
  • rat
  • endogenous neural stem cells
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