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Chinese Science Bulletin

, Volume 57, Issue 16, pp 1953–1958 | Cite as

An efficient and recyclable iron(III)-containing imidazolium salt catalyst for cross-coupling of aryl Grignard reagents with alkyl halides

  • ChunHui Yan
  • LinLin Wang
  • HuanHuan Gao
  • HongMei SunEmail author
  • Qi ShenEmail author
Open Access
Article Organic Chemistry

Abstract

1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride, [DIPrim]Cl, was used to produce a novel iron(III)-containing imidazolium salt [DIPrim][FeCl4], which included a N,N-diarylimidazolium cation (R = 2,6-diisopropylphenyl), [DIPrim]+, and tetrachloroferrate(III) anion, [FeCl4]. This compound was an effective and easy-to-use catalyst for the cross-coupling of aryl Grignard reagents with primary and secondary alkyl halides bearing β-hydrogens. After simply decanting the cross-coupling product in the ether layer, [DIPrim][FeCl4] could be reused in at least four successive runs without significant loss of catalytic activity.

Keywords

iron(III) complex imidazolium salt alkyl halide cross-coupling Grignard reagent 

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Copyright information

© The Author(s) 2012

Open AccessThis is an open access article distributed under the terms of the Creative Commons Attribution Noncommercial License (https://creativecommons.org/licenses/by-nc/2.0), which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

Authors and Affiliations

  1. 1.The Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials ScienceSoochow UniversitySuzhouChina

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