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Ortho-hydroxy assisted and copper-catalyzed oxidation of benzylic alcohol

  • Letter
  • Organic Chemistry
  • Published:
Chinese Science Bulletin

Abstract

An efficient and simple protocol for the synthesis of o-hydroxyarylketones has been developed. The reaction proceeds smoothly with catalytic amounts of copper catalyst under air atmosphere without ligands. This study indicates that the o-hydroxy plays an important role in the oxidation of alcohol to the corresponding carbonyl compounds.

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Authors and Affiliations

  1. Hefei National Laboratory for Physical Science at Microscale, Joint-Lab of Green Synthetic Chemistry and Department of Chemistry, University of Science and Technology of China, Hefei, 230026, China

    ChangFeng Wan, JinMin Fan, JinTang Zhang & ZhiYong Wang

Authors
  1. ChangFeng Wan
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  2. JinMin Fan
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  3. JinTang Zhang
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  4. ZhiYong Wang
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Corresponding author

Correspondence to ZhiYong Wang.

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Wan, C., Fan, J., Zhang, J. et al. Ortho-hydroxy assisted and copper-catalyzed oxidation of benzylic alcohol. Chin. Sci. Bull. 55, 2817–2819 (2010). https://doi.org/10.1007/s11434-010-3066-y

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  • DOI: https://doi.org/10.1007/s11434-010-3066-y

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