Skip to main content
SpringerLink
Log in

Bioactive titanium metal surfaces with antimicrobial properties prepared by anodic oxidation treatment

  • Published:
Science in China Series E: Technological Sciences Aims and scope Submit manuscript

Abstract

In order to endow titanium metals with bioactivity and antimicrobial properties, titanium plates were subjected to anodic oxidation treatment in NaCl solutions in this study. The treated titanium metals could induce apatite formation in the fast calcification solution, and osteoblasts on the treated titanium surfaces proliferated well as those on the untreated titanium metal surfaces. The treated metals could inhibit S. aureus growth in the microbial culture experiments. It was assumed that Ti-OH groups and Ti-Cl groups formed on the treated titanium surface were responsible for the bioactivity and antimicrobial properties of the metals. The anodic oxidation treatment was an effective way to prepare bioactive titanium surfaces with antimicrobial properties.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Campoccia D, Montanaro L, Arciola C R. The significance of infection related to orthopedic devices and issues of antibiotic resistance. Biomaterials, 2006, 27: 2331–2339

    Article  Google Scholar 

  2. Soriano A, Garcia R S, Mensa J. Management of prosthetic joint infection. Rev Med Microbiol, 2006, 17: 55–63

    Article  Google Scholar 

  3. Yuko F, Negar G K, Marcial L U, et al. Characterization of an in vitro model for evaluating the interface between skin and percutaneous biomaterials, Wound Rep Reg, 2006, 14: 484–491

    Article  Google Scholar 

  4. Leonard A M, Barry M F, Robert J S, et al. Guidline for the management of intravascular catheter related infections. Clin Infect Dis, 2001, 32: 1249–1272

    Article  Google Scholar 

  5. Yang B C, Uchida M, Kim H M, et al. Preparation of bioactive titanium metal via anodic oxidation treatment. Biomaterials, 2004, 25: 1003–1010

    Article  Google Scholar 

  6. Ikeda S, Igarashi T. Titanium plate anodization by discharging in NaCl, NaF and KI solution acquires antibacterial activity to oral bacteria. Jpn J Dent Mater, 2001, 20: 68–76

    Google Scholar 

  7. Wen H B, Wolke J G C, Wijn de J R, et al. Fast precipitation of calcium phosphate layers on titanium induced by simple chemical treatments. Biomaterials, 1997, 18: 1471–1478

    Article  Google Scholar 

  8. Wen H B, Wijn de J R, Cui F Z, et al. Preparation of bioactive Ti6Al4V surfaces by a simple method. Biomaterials, 1998, 19: 215–221

    Article  Google Scholar 

  9. Patel J, Salen L B, Martin G P, et al. Use of the MTT assay to evaluate the biocompatibility of beta-cyclodextrin derivatives with respiratory epithelial cells. J Pharm Pharmacol, 2006, 58(Suppl 1): A64–A64

    Google Scholar 

  10. Rose E, Jonas I, Kappert H F. Biocompatibility of orthodontic wires-in vitro assessment by MTT-test and corrosion-test. J Dent Res, 1998, 77: 824–824

    Google Scholar 

  11. Chen W, Roberts J T. Surface chemistry of TiCl4 on W (100). Surf Sci, 1996, 359: 93–106

    Article  Google Scholar 

  12. Xie Y T, Liu X Y, Huang A, et al. Improvement of surface bioactivity on titanium by water and hydrogen plasma immersion ion implantation. Biomaterials, 2005, 26: 6129–6135

    Article  Google Scholar 

  13. Yu J C, Zhang L Z, Zheng Z, et al. Synthesis and characterization of phosphated mesoporous titanium dioxide with high photocatalytic activity. Chem Mater, 2003, 15: 2280–2286

    Article  Google Scholar 

  14. Kokuboo T, Kim H M, Kawashita M. Novel bioactive materials with different mechanical properties. Biomaterials, 2003, 24: 2161–2175

    Article  Google Scholar 

  15. Liu X Y, Chu P K, Ding C X. Surface modification of titanium, titanium alloys, and related materials for biomedical applications. Mater Sci Eng R, 2004, 47: 49–212

    Article  Google Scholar 

  16. Kunzler T P, Drobek T, Schuler M, et al. Systematic study of osteoblast and fibroblast response to roughness by means of surface-morphology gradients. Biomaterials, 2007, 28: 2175–2182

    Article  Google Scholar 

  17. Guehennec Le L, Soueidan A, Layrolle P, et al. Surface treatments of titanium dental implants for rapid osseointegration. Dent Mater, 2007, 23: 844–854

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, China

    ChongXia Yue, BangCheng Yang & XingDong Zhang

  2. National Engineering Research Center in Biomaterials, Chengdu, 610064, China

    ChongXia Yue, BangCheng Yang & XingDong Zhang

Authors
  1. ChongXia Yue
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. BangCheng Yang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. XingDong Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to BangCheng Yang.

Additional information

Supported by the National Natural Science Foundation of China (Grant Nos. 50672062 and 30870615), Key Programs for Science and Technology Development of Sichuan Province, China (Grant No. 2008SZ0104) and Sichuan Youth Science & Technology Foundation, China (Grant No. 09ZQ026-033)

Rights and permissions

Reprints and permissions

About this article

Cite this article

Yue, C., Yang, B. & Zhang, X. Bioactive titanium metal surfaces with antimicrobial properties prepared by anodic oxidation treatment. Sci. China Ser. E-Technol. Sci. 52, 2269–2274 (2009). https://doi.org/10.1007/s11431-009-0223-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11431-009-0223-0

Keywords

Search

Navigation