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Langzeiteffekte von Diabetespräventionsmaßnahmen

Gibt es Effekte über die reine Diabetesprävention hinaus?

Long-term effects of diabetes prevention measures

Are there effects beyond pure diabetes prevention?

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Der Diabetologe Aims and scope

Zusammenfassung

Diabetesprävention kann durch Lebensstilintervention, Pharmakotherapie oder eine Kombination aus beiden erreicht werden. In einer Vielzahl von wegweisenden randomisierten, kontrollierten Studien wurde festgestellt, dass Präventionsprogramme das Typ-2-Diabetes-Risiko während der Interventionsphase effektiv senken und in den Jahren danach niedrig halten. Darüber hinaus wurde in diesen Untersuchungen auch eine Reduktion weiterer Morbiditätsrisiken, wie des Risikos kardiovaskulärer und maligner Erkrankungen, nachgewiesen. In vorliegender Übersichtsarbeit soll ein Überblick über die Langzeitergebnisse mehrere Jahre nach Abschluss von Diabetespräventionsprogrammen gegeben werden.

Abstract

Diabetes prevention can be achieved through lifestyle intervention, pharmacotherapy, or a combination of both. A large number of pioneering, randomized controlled studies have shown that prevention programs can effectively reduce the risk of type 2 diabetes during the intervention phase and keep it low in the years after the intervention. In addition, these studies have also shown a reduction in other morbidity risks, such as the risk of cardiovascular diseases and cancer. The goal of this review is to provide a review of the long-term results several years after the end of diabetes prevention programs.

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Authors and Affiliations

  1. Institut für Diabetesforschung und Metabolische Erkrankungen (IDM) des Helmholtz Zentrums München, Universität Tübingen, Otfried-Müller-Str. 10, 72076, Tübingen, Deutschland

    Corinna Dannecker, Julia Hummel & Louise Fritsche

  2. Deutsches Zentrum für Diabetesforschung (DZD), Neuherberg, Deutschland

    Corinna Dannecker, Julia Hummel & Louise Fritsche

Authors
  1. Corinna Dannecker
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  2. Julia Hummel
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  3. Louise Fritsche
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Correspondence to Louise Fritsche.

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Interessenkonflikt

C. Dannecker, J. Hummel und L. Fritsche geben an, dass kein Interessenkonflikt besteht.

Für diesen Beitrag wurden von den Autoren keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.

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Dannecker, C., Hummel, J. & Fritsche, L. Langzeiteffekte von Diabetespräventionsmaßnahmen. Diabetologe 16, 215–219 (2020). https://doi.org/10.1007/s11428-020-00593-z

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  • DOI: https://doi.org/10.1007/s11428-020-00593-z

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