Skip to main content
SpringerLink
Log in

Auswirkungen von Liraglutid auf die Hirnaktivität

Effect of liraglutide on brain activity

  • Journal Club
  • Published:
Der Diabetologe Aims and scope

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. Schlögl H et al (2013) Exenatide-induced reduction in energy intake is associated with increase in hypothalamic connectivity. Diabetes Care 36:1933–1940

    Article  PubMed  PubMed Central  Google Scholar 

  2. Larsen PJ, Tang-Christensen M, Holst JJ, Orskov C (1997) Distribution of glucagon-like peptide-1 and other preproglucagonderived peptides in the rat hypothalamus and brainstem. Neuroscience 77:257–270

    Article  CAS  PubMed  Google Scholar 

  3. Hunter K, Holscher C (2012) Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis. BMC Neurosci 13:33

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Holst JJ (2007) The physiology of glucagon-like peptide 1. Physiol Rev 87:1409–1439

    Article  CAS  PubMed  Google Scholar 

  5. Sisley S, Gutierrez-Aguilar R, Scott M, D’Alessio DA, Sandoval DA, Seeley RJ (2014) Neuronal GLP1R mediates liraglutide s anorectic but not glucose-lowering effect. J Clin Invest 124:2456–2463

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Heppner KM, Kirigiti M, Secher A et al (2015) Expression and distribution of glucagon-like peptide-1 receptor mRNA, protein and binding in the male nonhuman primate (Macaca mulatta) brain. Endocrinology 156:255–267

    Article  PubMed  Google Scholar 

  7. Wang XF, Liu JJ, Xia J, Liu J, Mirabella V, Pang ZP (2015) Endogenous glucagon-like peptide-1 suppresses high-fat food intake by reducing synaptic drive onto mesolimbic dopamine neurons. Cell Rep 12:726–733

    Article  PubMed  PubMed Central  Google Scholar 

  8. Pyke C, Heller RS, Kirk RK et al (2014) GLP-1 receptor localization in monkey and human tissue: novel distribution revealed with extensively validated monoclonal antibody. Endocrinology 155:1280–1129

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Medizinische Klinik – Diabetologie, Gemeinschaftskrankenhaus Havelhöhe, Kladower Damm 221, 14089, Berlin, Deutschland

    M. Jecht

Authors
  1. M. Jecht
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to M. Jecht.

Ethics declarations

Interessenkonflikt

M. Jecht gibt an, dass kein Interessenkonflikt besteht.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Jecht, M. Auswirkungen von Liraglutid auf die Hirnaktivität. Diabetologe 12, 428–429 (2016). https://doi.org/10.1007/s11428-016-0133-2

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11428-016-0133-2

Search

Navigation