Skip to main content
Log in

Diabetespatienten mit chronischer Niereninsuffizienz

Neue Aspekte in Diagnostik und Therapie

Diabetes patients with chronic renal disease

New aspects in diagnostics and therapy

  • CME Zertifizierte Fortbildung
  • Published:
Der Diabetologe Aims and scope

Zusammenfassung

Mit der Publikation der Nationalen VersorgungsLeitlinie „Nierenerkrankungen bei Diabetes im Erwachsenenalter“ 2010 wurde ein Meilenstein im Versorgungsmanagement dieser Patientengruppe erreicht. Die Beurteilung der qualitativen Umsetzung dieser Leitlinie und ihrer Auswirkung auf wesentliche Ergebnisparameter steht gegenwärtig aus. Mit der neuen Leitlinie der Kidney Disease: Improving Global Outcomes (KDIGO, 2012) zur Evaluation und zum Management der chronischen Nierenkrankheit sowie ergänzenden internationalen Leitlinien werden wesentliche Aspekte der Klassifikation, Prognoseabschätzung, Behandlungsziele und interdisziplinären Kooperation angesprochen, die für die Betreuung von Diabetespatienten mit Nierenerkrankungen von grundsätzlicher Bedeutung sind. Dieser Beitrag fasst einige dieser Aspekte zusammen mit dem Ziel, sie in das aktuelle Versorgungsmanagement zu integrieren.

Abstract

With the publication in 2010 of the German guidelines on renal diseases in adult diabetes mellitus, a milestone in the care of this patient group was achieved. The evaluation of quality and clinical results of these guidelines in daily practice is currently pending. The international guidelines on the evaluation and management of chronic kidney disease as developed by the “kidney disease: improving global outcomes (KDIGO)” initiative in 2012 and supplementary international guidelines significantly influenced the care for these patients with the focus on prognosis, risk stratification, therapeutic goals and interdisciplinary cooperation. The aim of this article is the implementation some important aspects of these guidelines into the current treatment and management of patients with diabetes mellitus and renal disease.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1
Abb. 2
Abb. 3
Abb. 4

Literatur

  1. Nationale VersorgungsLeitlinie Nierenerkrankungen im Erwachsenenalter. http://www.awmf.org/uploads/tx_szleitlinien/nvl-001dl_S3_Nierenerkrankungen_bei_Diabetes_Erwachsene_2013-05_01.pdf. Zugegriffen: 19. Sept. 2014

  2. European Society of Hypertension, European Society of Cardiology (ESH/ESC) (2013) Guidelines for the management of arterial hypertension. http://www.esh2013.org/wordpress/wp-content/uploads/2013/06/ESC-ESH-Guidelines-2013.pdf. Zugegriffen: 13. Mai 2014

  3. Kidney Disease: Improving Global Outcomes (2012) Clinical practice guideline for the evaluation and management of chronic kidney disease (2013) Kidney Int Suppl 3(1). http://www.kidney.org/professionals/KDOQI/guidelines_diabetesUp/diabetes-ckd-update-2012.pdf. Zugegriffen: 13. Mai 2014

  4. Kidney Disease Outcomes Quality Initiative (2012) Clinical practice guideline for diabetes and CKD: update 2012. http://www.kidney.org/professionals/KDOQI/guidelines_diabetesUp/diabetes-ckd-update-2012.pdf. Zugegriffen: 13. Mai 2014

  5. Kidney Disease: Improving Global Outcomes (2013) Clinical practice guideline for lipid management in chronic kidney disease. http://www.kdigo.org/clinical_practice_guidelines/Lipids/KDIGO%20Lipid%20Management%20Guideline%202013.pdf. Zugegriffen: 22. Juli 2014

  6. Pommer W (2009) Nephropathie bei Diabetes mellitus. Diabetologe 5:563–575

    Article  Google Scholar 

  7. Ramirez SP, McCullough KP, Thumma JR et al (2012) Hemoglobin A(1c) levels and mortality in the diabetic hemodialysis population: findings from the Diabetes Outcomes and Practice Patterns Study (DOPPS). Diabetes Care 35:2527–2532

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  8. Vijan S, Sussman JB, Yudkin JS, Hayward RA (2014) Effect of patients‘ risks and preferences on health gains with plasma glucose level lowering in type 2 diabetes mellitus. JAMA Intern Med 174(8):1227–1234 DOI 10.10002/jamainternmed.2014.2894

    Article  PubMed  Google Scholar 

  9. Boer IH de; DCCT/EDIC Research Group (2014) Kidney disease and related findings in the diabetes control and complication trial/epidemiology of diabetes interventions and complications study. Diabetes Care 37:24–30

    Article  PubMed  Google Scholar 

  10. Charlson ME, Pompei P, Ales KL et al (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40:373–383

    Article  PubMed  CAS  Google Scholar 

  11. Inzucchi SE, Bergenstal RM, Buse JB et al (2012) Management of hyperglycemia in type 2 diabetes: a patient centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetologica 55:1577–1596

    Article  CAS  Google Scholar 

  12. Inzucchi SE, Bergenstal RM, Buse JB et al (2012) Management of hyperglycemia in type 2 diabetes: a patient centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 35:1364–1379

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  13. Zeyfang A, Bahrmann A, Wernecke J (2010) Diabetes mellitus im Alter. DDG Praxisleitlinie. Diabetologie 5(Suppl 2):166–171

    Article  Google Scholar 

  14. Abaterusso C, Lupo A, Ortalda V et al (2008) Treating elderly people with diabetes and stages 3 and 4 chronic kidney disease. Clin J Am Soc Nephrol 3:1185–1194

    Article  PubMed  Google Scholar 

  15. Stahn A, Pistroch F, Ganz X et al (2014) Relationship between hypoglycemic episodes and ventricular arrhythmias in patients with type 2 diabetes and cardiovascular disease: silent hypoglycemias and silent arrhythmias. Diabetes Care 37:516–525

    Article  PubMed  CAS  Google Scholar 

  16. Moen MF, Zhan M, Hsu VD et al (2009) Frequency of hypoglycemia and its significance in chronic kidney disease. Clin J Am Soc Nephrol 4:1121–1127

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  17. Dunkler D, Dehghan M, Teo KK et al (2013) Diet and kidney disease in high-risk individuals with type 2 diabetes. JAMA Int Med 14:1682–1692

    Google Scholar 

  18. Hasslacher C (2013) Antidiabetische Therapie bei Niereninsuffizienz. Diabetologe 9:613–621

    Article  Google Scholar 

  19. Kovesdy CP, Park JC, Kalantar-Zadeh K (2010) Glycemic control and burnt out diabetes in ESRD. Semin Dial 23:146–156

    Google Scholar 

  20. Takahashi A, Kubote T, Shibahara N et al (2004) The mechanism of hypoglycemia caused by hemodialysis. Clin Nephrol 62:362–368

    Article  PubMed  CAS  Google Scholar 

  21. Navaneethan SD, Nigwekar SU, Sehgal AR, Stripolli GF (2009) Aldosterone antagonists for preventing the progression: a systematic review and meta-analysis. Clin J Am Soc Nephrol 4:542–551

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  22. Al-Hamid A, Ghaleb M, Aljadhey H, Aslanpour Z (2013) A systematic review of hospitalisation resulting from medicine related problems in adult patients. Br J Clin Pharmacol 28. DOI 10.1111/bcp.12293

  23. Hemmelgarn BR, Zhang J, Manns BJ et al (2006) Progression of kidney dysfunction in the community-dwelling elderly. Kidney Int 69:2155–2161

    Article  PubMed  CAS  Google Scholar 

  24. PatientenLeitlinie zur Nationalen VersorgungsleitLinie Nierenerkrankungen bei Diabetes im Erwachsenenalter. http://www.versorgungsleitlinien.de/patienten/pdf/nvl-t2dm-nephropathie-patienten-1.0.pdf. Zugegriffen: 13. Mai 2014

Download references

Einhaltung ethischer Richtlinien

Interessenkonflikt. W. Pommer und B. Oser geben an, dass kein Interessenkonflikt besteht. Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to W. Pommer.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Pommer, W., Oser, B. Diabetespatienten mit chronischer Niereninsuffizienz. Diabetologe 10, 589–602 (2014). https://doi.org/10.1007/s11428-014-1274-9

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11428-014-1274-9

Schlüsselwörter

Keywords

Navigation