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Diabetes und Depression

Risiken und Zusammenhänge

Diabetes and depression

Risks and related factors

  • Leitthema
  • Published:
Der Diabetologe Aims and scope

Zusammenfassung

Menschen mit Diabetes haben gegenüber der Allgemeinbevölkerung ein deutlich erhöhtes Risiko für die Entwicklung einer Depressivität (subklinische Depression) oder Depression (klinische Depression, entsprechen den ICD- bzw. DSM-Kriterien), welche eine bedeutsame Barriere für das Erreichen der Therapieziele des Diabetes darstellen. Diabetespatienten mit einer Depression weisen im Vergleich zu nichtdepressiven Patienten ein ungünstigeres Krankheits- und Therapieverhalten, eine eingeschränkte Lebensqualität, eine schlechtere Blutzuckereinstellung, ein erhöhtes Risiko für die Entwicklung von Folgeerkrankungen sowie auch ein deutlich erhöhtes Mortalitätsrisiko auf. Als Ursache hierfür werden sowohl neuroendokrinologische Veränderungen, krankheitsspezifische Belastungen, direkte wie indirekte Auswirkungen der Blutzuckerwerte auf die Stimmung als auch dysfunktionale Bewältigungsfertigkeiten und -stile seitens des Patienten diskutiert. Obwohl wirksame Interventionen zur Depressionsbehandlung bei Diabetespatienten zu Verfügung stehen, werden in der Praxis noch zu wenige Patienten mit einer Depressionen diagnostiziert und adäquat behandelt.

Abstract

Compared with the general population diabetic patients have a clearly increased risk of suffering from depressive symptoms (subclinical form) or to develop depression (according the ICD or DSM criteria), which can represent a significant barrier to achieving the goals of diabetes therapy. The co-morbidity of depression and diabetes has a negative impact on the patient’s disease management, quality of life, glycaemic control, risk for late complications and mortality. Neuroendocrine alterations, disease-specific impact, direct and indirect effects on glycaemic control as well as impaired coping ability and strategies are all discussed as possible causes. Although effective interventions for the management of depression in diabetic patients exist, in clinical practise, patients with depression remain to a large extent unrecognised and untreated.

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Authors and Affiliations

  1. Diabetes-Zentrum Mergentheim, Forschungsinstitut Diabetes-Akademie Bad Mergentheim (FIDAM), Theodor-Klotzbücher-Str. 12, 97980, Bad Mergentheim, Deutschland

    B. Kulzer Dipl.-Psych. & N. Hermanns

  2. Klinik für Psychosomatik und Psychotherapie der Justus-Liebig-Universität Gießen, Gießen, Deutschland

    J. Kruse

Authors
  1. B. Kulzer Dipl.-Psych.
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  2. N. Hermanns
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  3. J. Kruse
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Correspondence to B. Kulzer Dipl.-Psych..

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Kulzer, B., Hermanns, N. & Kruse, J. Diabetes und Depression. Diabetologe 6, 255–265 (2010). https://doi.org/10.1007/s11428-009-0531-9

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  • DOI: https://doi.org/10.1007/s11428-009-0531-9

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