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Gehirn und metabolisches Syndrom

The brain and the metabolic syndrome

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Zusammenfassung

Wir zeigen eine neue Sichtweise, in der das Gehirn vor allem seinen eigenen hohen Energiebedarf sicherstellt (engl. „selfish brain“). Dazu fordert das Gehirn (zerebrale Hemisphären, Hypothalamus) aktiv Energie entweder aus dem Körper (Allokation) oder aus der Umwelt an (Nahrungsaufnahme). Wenn diese zerebrale Energieanforderung gestört ist, entstehen Erkrankungen wie Adipositas, das metabolische Syndrom und Typ-2-Diabetes-mellitus.

Abstract

We present here the new perspective that the brain primarily ensures its own high energy requirements (“selfish brain”). The brain (cerebral hemispheres, hypothalamus) actively requests energy either from the body (allocation) or the environment (food intake). Disruption of one of the cerebral energy request pathways leads to illnesses such as obesity, metabolic syndrome and type-2 diabetes.

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  1. Medizinische Klinik 1, Universität zu Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Deutschland

    A. Peters, C. Hubold & H. Lehnert

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  1. A. Peters
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  2. C. Hubold
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  3. H. Lehnert
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Correspondence to A. Peters.

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Peters, A., Hubold, C. & Lehnert, H. Gehirn und metabolisches Syndrom. Diabetologe 4, 189–195 (2008). https://doi.org/10.1007/s11428-008-0228-5

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  • DOI: https://doi.org/10.1007/s11428-008-0228-5

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