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Therapie mit Insulinpumpen

Treatment with insulin pumps

  • Leitthema
  • Published:
Der Diabetologe Aims and scope

Zusammenfassung

Die Insulinpumpentherapie (CSII) wird zur Behandlung des Typ-1-Diabetes besonders in der Pädiatrie in den letzten Jahren zunehmend eingesetzt. Obwohl randomisierte Studien nicht durchgängig eine Verbesserung des HbA1c und eine Senkung der Hypoglykämierate zeigen, sind bei richtiger Patientenauswahl die Erfahrungen überwiegend positiv. Die Behandlung mit den modernen programmierbaren Pumpen ist im Prinzip nicht schwieriger als eine intensivierte konventionelle Insulintherapie (ICT). Wegen der noch deutlicheren Trennung von Basal- und Prandialinsulinbedarf ist bei der CSII das Prinzip der differenzierten Prandial- und Basalinsulinsubstitution noch klarer erkennbar und darum auch einfacher umsetzbar. Ohne Zweifel können mit ihr gleichmäßigere Insulinspiegel erreicht werden als mit der ICT. ICT und CSII haben sich bei Kindern, Jugendlichen und Erwachsenen als 2 gleichwertige Varianten der intensivierten Insulintherapie erwiesen, die heute unstrittig als die Therapie der Wahl bei Typ-1-Diabetes gilt.

Abstract

Insulin pump therapy (CSII) is used with increasing frequency in type 1 diabetes, especially in paediatric patients. While not all randomized studies have shown better glycaemic control or a lower rate of hypoglycaemia, clinical experience of CSII is generally positive when patients are carefully selected. In principle, treatment with modern programmable pumps (CSII) is no more difficult than a conventional intensified multiple injection therapy (ICT). Owing to the clear differentiation made between prandial and basal insulin requirements, insulin substitution is more clearly recognizable and therefore easier to achieve.CSII definitely leads to more nearly constant insulin levels. Therefore, ICT and CSII have become established as equally valuable forms of intensified insulin therapy, which is now recognized as the therapy of choice in type 1 diabetes.

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Authors and Affiliations

  1. Diabeteszentrum für Kinder und Jugendliche, Kinderkrankenhaus auf der Bult, Janusz-Korczak-Allee 12, 30173 , Hannover

    T. Danne, W. von Schütz, C. Nestoris, N. Datz & O. Kordonouri

  2. Abteilung für Medizinische Psychologie, OE 5430, Medizinische Hochschule Hannover

    K. Lange

Authors
  1. T. Danne
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  2. W. von Schütz
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  3. K. Lange
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  4. C. Nestoris
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  5. N. Datz
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  6. O. Kordonouri
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Correspondence to T. Danne.

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Danne, T., von Schütz, W., Lange, K. et al. Therapie mit Insulinpumpen. Diabetologe 2, 321–331 (2006). https://doi.org/10.1007/s11428-006-0060-8

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  • DOI: https://doi.org/10.1007/s11428-006-0060-8

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