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Prof. Changtao Jiang, vice dean of the School of Basic Medical Sciences of Peking University, chairman of the Department of Immunology. He proposed a new theory of “Intestinal microbial enzymes regulate host homeostasis across kingdoms.” He presented for the first time the concept of gut Microbial-Host isozymes (MHIs), identified the bacterial-derived isozyme dipeptidyl peptidase 4 (DPP4) and highlighted its important role in metabolic diseases. He identified an endogenous nicotine-degrading gut microbiota and proposed a novel intervention strategy for gut bacteria to alleviate metabolic diseases through the nicotine-degrading enzyme NicX. He revealed the role of various bile acid metabolizing enzymes in the regulation of metabolic diseases. In the past 5 years, Prof. Changtao Jiang has published more than 20 SCI papers in Science, Nature, Nature Medicine (3 articles), Cell Metabolism (3 articles) and other journals as the corresponding author. Among these, four articles were selected as highly cited papers, one article received an F1000 Prime recommendation with the highest rating score, and eight articles gained recommendations from internationally renowned scholars and contemporaneous reviews. He received the Xplorer Prize, China’s top 10 advances in life sciences in 2023, the China Youth Science and Technology Award, the Shulan Medical Young Scientist Award, the Chinese-American Diabetes Association (CADA) Young Investigator Award, the Mao Yisheng Beijing Youth Science and Technology Award and other awards. He is in charge of the projects supported by the Key Program of the National Natural Science Foundation of China, the Major Research Plan of the National Natural Science Foundation of China and the National Key Research and Development Program of China. He is the principal investigator for a project supported by the Science Fund for Creative Research Groups of the National Natural Science Foundation of China.
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Jiang, C. Progress in gut microbiota-host interaction. Sci. China Life Sci. (2024). https://doi.org/10.1007/s11427-024-2577-0
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DOI: https://doi.org/10.1007/s11427-024-2577-0